Gobarani Rukshar K, Weeks Gregory R, Abramson Michael J, Bonevski Billie, Paul Eldho, Webb Ashley, Kirsa Sue, Smith Brian J, Thomas Dennis, Perinpanathan Sharmilla, Parkinson Jacqueline, Meanger Darshana, Coward Lisa, Rofe Olivia, Lee Paula, George Johnson
Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Pharmacy Department, Barwon Health, Geelong, Victoria, Australia.
Health Promot J Austr. 2023 Apr;34(2):420-428. doi: 10.1002/hpja.658. Epub 2022 Sep 17.
Understanding smoking behaviors in hospital patients who smoke may improve inpatient cessation treatments. This study aimed to describe smoking-related behaviors, past-quit attempts, and self-reported difficulties experienced in quitting among those who enrolled in a smoking cessation trial of varenicline.
Baseline data were obtained from adult hospitalized smokers (average ≥ 10 cigarettes/day in 4-weeks prior to hospitalization) who enrolled in a randomized, placebo-controlled trial of varenicline ± nicotine lozenges at five Australian public hospitals. A logistic regression model tested the association between participant characteristics and quitting in the previous 12 months.
Participants' (n = 320; 57% male, 52.5 ± 12.1 years old) motivation and confidence in quitting were high. A total of 120 participants (37.5%) had attempted quitting in the previous 12-months. Prior hospitalization (P = .008) and employment status (P = .015) were significantly associated with past quit attempts. No statistically significant differences were noted in the reason for hospitalization or the level of nicotine dependence between participants who attempted quitting in the previous 12 months and their counterparts. Smoking cessation pharmacotherapy was used by 55% of those attempting to quit; nicotine replacement therapy (65.2%) and varenicline (16.7%) most common. Stress or anxiety, urges to smoke and a lack of motivation were the difficulties experienced in past quit attempts.
Those who had a prior hospitalization and were unemployed had significantly greater odds of reporting past quit attempts. Further research is needed to investigate the degree of adherence among inpatient smokers with the smoke-free hospital policies and the frequency of NRT provision and uptake on admission.
了解住院吸烟患者的吸烟行为可能会改善住院戒烟治疗。本研究旨在描述参加伐尼克兰戒烟试验者的吸烟相关行为、既往戒烟尝试以及自我报告的戒烟困难。
基线数据来自澳大利亚五家公立医院的成年住院吸烟者(住院前4周平均每天吸烟≥10支),这些吸烟者参加了一项伐尼克兰±尼古丁含片的随机、安慰剂对照试验。采用逻辑回归模型检验参与者特征与过去12个月内戒烟之间的关联。
参与者(n = 320;57%为男性,年龄52.5±12.1岁)戒烟的动机和信心较高。共有120名参与者(37.5%)在过去12个月内尝试过戒烟。既往住院史(P = 0.008)和就业状况(P = 0.015)与既往戒烟尝试显著相关。在过去12个月内尝试戒烟的参与者与其未尝试戒烟的同行之间,住院原因或尼古丁依赖程度没有统计学上的显著差异。55%尝试戒烟者使用了戒烟药物治疗;最常用的是尼古丁替代疗法(65.2%)和伐尼克兰(16.7%)。压力或焦虑、吸烟冲动和缺乏动力是过去戒烟尝试中遇到的困难。
有既往住院史且失业的人报告既往戒烟尝试的几率显著更高。需要进一步研究调查住院吸烟者对无烟医院政策的遵守程度以及入院时提供和使用尼古丁替代疗法的频率。