Shijiazhuang Obstetrics and Gynecology Hospital Ultrasonography Lab, 050000, China.
Gucheng County Hospital of Hebei Province Obstetrics and Gynecology Ultrasound Department, 253800, China.
Comput Math Methods Med. 2022 Aug 27;2022:6565109. doi: 10.1155/2022/6565109. eCollection 2022.
To offer a baseline for clinical diagnosis, echocardiography was performed to evaluate the disparities in heart function comparing pregnant women with diabetes mellitus (GDM) and ordinary pregnant women.
A prospective case-control study is being conducted on pregnant women with or without gestational diabetes. The sample size for both the intervention and control groups is the same: no diabetes diagnosis or previous forms, a single pregnancy, and no issues (such as preeclampsia or fetal growth restriction). The females were all subjected to routine echocardiograms to examine the morphology and function of their left and right hearts.
In the research, 51 women with GDM and 50 healthy controls volunteered. Women with GDM had a significantly higher heartrate (82 ± 9 vs. 74 ± 8), left ventricular (LV) relative wall thickness (0.39 ± 0.06 vs. 0.31 ± 0.07; < 0.001), LV early diastolic transmitral valve velocity (E) (0.79 ± 0.14 vs. 0.72 ± 0.13 m/s; = 0.031), and LV late diastolic implementing regulations valve velocity (0.6). Speckle-tracking analysis showed significant decrease in LV right ventricular (RV). A study indicated a reduced pulmonary acceleration time (59 ± 9 vs. 68 ± 12 ms; = 0.001), RV E/A ratio (1.21 ± 0.19 vs. 1.31 ± 0.31; = 0.022), and a greater RV myocardial systolic annular velocity (0.17 ± 0.03 vs. 0.12 ± 0.03; = 0.023).
Our results revealed that the heart function of diabetic pregnant women differed considerably from that of the control group, such as LV-RWT, LV diastolic transmitral valve speed, and LV late diastolic transmitral valve speed. Given these results, further research into the postpartum cardiovascular healing of pregnant women with gestational diabetes mellitus is required.
通过超声心动图评估妊娠糖尿病(GDM)孕妇与普通孕妇心功能的差异,为临床诊断提供基线参考。
采用前瞻性病例对照研究,纳入妊娠期合并或不合并糖尿病的孕妇。干预组和对照组的样本量相同:无糖尿病诊断或既往病史、单胎妊娠且无其他问题(如子痫前期或胎儿生长受限)。所有女性均接受常规超声心动图检查,以评估其左右心的形态和功能。
研究共纳入 51 例 GDM 孕妇和 50 例健康对照者。GDM 孕妇的心率(82 ± 9 比 74 ± 8)、左心室(LV)相对室壁厚度(0.39 ± 0.06 比 0.31 ± 0.07;<0.001)、LV 舒张早期二尖瓣瓣口血流速度(E)(0.79 ± 0.14 比 0.72 ± 0.13m/s;=0.031)和 LV 舒张晚期二尖瓣瓣口血流速度(0.6)均较高。斑点追踪分析显示 LV 右心室(RV)功能明显下降。研究表明,肺动脉加速时间(59 ± 9 比 68 ± 12ms;=0.001)、RV E/A 比值(1.21 ± 0.19 比 1.31 ± 0.31;=0.022)和 RV 心肌收缩环速度(0.17 ± 0.03 比 0.12 ± 0.03;=0.023)均降低。
我们的研究结果表明,与对照组相比,糖尿病孕妇的心功能存在明显差异,如 LV-RWT、LV 舒张早期二尖瓣瓣口血流速度和 LV 舒张晚期二尖瓣瓣口血流速度等。鉴于这些结果,需要进一步研究妊娠期糖尿病孕妇产后心血管的恢复情况。