环二核苷酸信号的完善 c-di-AMP 的作用和机制。
Rounding out cyclic dinucleotide signaling in A role and a mechanism for c-di-AMP.
机构信息
Department of Chemistry and Biochemistry, Old Dominion University, 4501 Elkhorn Avenue, Norfolk, VA 23529, USA. Email:
出版信息
Sci Signal. 2022 Sep 6;15(750):eadd3937. doi: 10.1126/scisignal.add3937.
PMID:36067335
Abstract
The second messenger c-di-AMP contributes to various homeostatic and stress responses in bacteria. In this issue of , Oberkampf . have identified it as a mediator of osmotic stress and bile salt resistance in the opportunistic pathogen , with additional roles in cell wall homeostasis and biofilm formation.
摘要
第二信使 c-di-AMP 有助于细菌的各种动态平衡和应激反应。在本期的 中，Oberkampf 等人发现它是机会性病原体耐渗透压和胆汁盐的介质，在细胞壁动态平衡和生物膜形成方面具有额外的作用。
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