Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Gyeonggi-do 13496, Republic of Korea.
Oral Oncol. 2022 Nov;134:106103. doi: 10.1016/j.oraloncology.2022.106103. Epub 2022 Sep 5.
Recurrent pleomorphic adenoma (RPA) is a challenging disease because of difficulty in reoperation, a high rate of postoperative facial palsy, and potential malignant transformation. The optimal management of RPA is still arguable regarding the surgical extent and the necessity of radiotherapy. Therefore, this study compared the complication and re-recurrence rates of superficial versus total parotidectomy in a prospective cohort of 29 patients with RPA. Two surgical techniques were allocated to consecutive patients without randomization and blinding processes. Total parotidectomy was applied to lesions in deep or both lobes. Most early and late complication rates were statistically comparable between the two groups (P > 0.05). Transient and permanent facial nerve paralysis frequently occurred in 55 % and 14 % of all cases, respectively, without statistical difference between the two groups (P > 0.5). Only one patient (3 %) had re-recurrence after superficial parotidectomy during the mean follow-up of 89 months. Superficial or total parotidectomy is recommended to reduce the risk of further recurrence in patients with RPA.
复发性多形性腺瘤(RPA)是一种具有挑战性的疾病,因为其在再次手术时难度较大,术后面瘫发生率较高,且有潜在恶变的可能。RPA 的最佳治疗方案仍存在争议,主要涉及手术范围和放疗的必要性。因此,本研究前瞻性地比较了 29 例 RPA 患者中,行腮腺浅叶切除术与腮腺全叶切除术的并发症和复发率。这两种手术技术没有经过随机和盲法处理,分配给连续的患者。腮腺全叶切除术适用于深叶或双叶的病变。两组之间大多数早期和晚期并发症发生率均无统计学差异(P>0.05)。所有病例中,暂时性和永久性面神经瘫痪分别频繁发生于 55%和 14%的患者中,两组之间无统计学差异(P>0.5)。在平均 89 个月的随访中,仅 1 例(3%)患者在接受腮腺浅叶切除术后面临复发。建议对 RPA 患者行腮腺浅叶切除术或腮腺全叶切除术,以降低进一步复发的风险。