Ruthes Elena M P, Lenardt Brenda C C, Lass André Domingos, Petroski Carlos Alberto, de Mello Maria Fernanda, de Andrade Junior Antonio Beira, Souza Carlos José F, de Matos Oslei, Castelo-Branco Camil
Laboratory for Studies in Biomedical Engineering and Health, Academic Study in Bariatric Surgery Group (ASBS), Federal University of Technology, Curitiba, Brazil.
Laboratory of Exercise Biochemistry in Health, Graduate Program in Health Sciences, School of Medicine, Pontifícia Universidade Católica do Paraná, Curitiba, Brazil.
Gynecol Endocrinol. 2022 Oct;38(10):868-873. doi: 10.1080/09513590.2022.2119956. Epub 2022 Sep 6.
To assess the effect of bariatric surgery on the lean mass of women after one year of the procedure, comparing its outcomes upon the classification from both the Foundation of the National Institutes of Health (FNIH) and the European Working Group on Sarcopenia in the Elderly People (EWGSOP). : Twenty-eight obese women aged 40.5 ± 9.8 yrs who underwent Roux-en-Y gastric bypass (RYGB) were included. 27 of them were reassessed after 6 months of surgery, and 16 completed the one-year follow-up. Pre-sarcopenia condition was assessed through a handgrip strength test and body composition by dual-energy X-ray absorptiometry (DXA). Total body mass, body mass index, and lean mass (LM) were collected prior to, 6 and 12 months after RYGB surgery. : All subjects reassessed after 12 months were diagnosed with pre-sarcopenia according to the FNIH classification criteria, while according to the EWGSOP2 Consensus they presented normal values. LM represented 14% of the influence on handgrip strength ( = .049) after 6 months of surgery; however, its influence on strength after 12 months increased to 30% ( = .028). : The FNIH classification is the most effective criteria since it uses LM content as the first test, considering that strength capacity needs more time to be affected by the surgical procedure. On the other hand, the EWGSOP2 classification should not be applied to determine the loss of LM in younger populations regardless of what may have caused such changes.
为评估减重手术后一年对女性去脂体重的影响,根据美国国立卫生研究院基金会(FNIH)和欧洲老年人肌肉减少症工作组(EWGSOP)的分类标准比较其结果。纳入28名年龄为40.5±9.8岁、接受了Roux-en-Y胃旁路术(RYGB)的肥胖女性。其中27人在术后6个月进行了重新评估,16人完成了一年的随访。通过握力测试和双能X线吸收法(DXA)评估肌肉减少症前期状况。在RYGB手术前、术后6个月和12个月收集总体重、体重指数和去脂体重(LM)。根据FNIH分类标准,所有在12个月后重新评估的受试者均被诊断为肌肉减少症前期,而根据EWGSOP2共识,他们的各项指标均正常。术后6个月时,LM对手握力的影响占14%(P = 0.049);然而,术后12个月时其对握力的影响增加到30%(P = 0.028)。由于FNIH分类标准将LM含量作为首要检测指标,考虑到力量能力受手术影响需要更多时间,因此它是最有效的标准。另一方面,无论导致这些变化的原因是什么,EWGSOP分类标准都不适用于确定年轻人群中LM的损失情况。