中草药甘草的化学分析：更新综述。
Chemical analysis of the Chinese herbal medicine licorice (Gan-Cao): An update review.
机构信息
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, China.
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, 38 Xueyuan Road, Beijing, 100191, China.
出版信息
J Ethnopharmacol. 2022 Dec 5;299:115686. doi: 10.1016/j.jep.2022.115686. Epub 2022 Sep 5.
ETHNOPHARMACOLOGICAL RELEVANCE
Licorice, called Gan-Cao in China, is one of the most popular traditional herbal medicines. It is derived from the dried roots and rhizomes of Glycyrrhiza uralensis, G. glabra, and G. inflata. Licorice is recorded in the pharmacopoeias of China, Japan, US, and Europe.
AIM
This review updates research progress of licorice from the perspectives of chemical analysis, quality evaluation, drug metabolism, and pharmacokinetic studies from 2009 to April 2022.
MATERIALS AND METHODS
Both English and Chinese literatures were collected from databases including PubMed, Elsevier, Web of Science, and CNKI (Chinese). Licorice, extraction, structural characterization/identification, quality control, metabolism, and pharmacokinetics were used as keywords.
RESULTS
Newly developed analytical methods, including LC/UV, 2DLC, LC/MS, GC/MS, and mass spectrometry imaging (MSI) for chemical analysis of licorice were summarized.
CONCLUSION
This review provides a comprehensive summary on chemical analysis of licorice.
民族药理学相关性
甘草，在中国被称为“甘草”，是最受欢迎的传统草药之一。它来源于甘草、光果甘草和胀果甘草的干燥根和根茎。甘草被收录在中国、日本、美国和欧洲的药典中。
目的
本综述从化学分析、质量评价、药物代谢和药代动力学研究等方面更新了 2009 年至 2022 年 4 月期间甘草的研究进展。
材料和方法
从 PubMed、Elsevier、Web of Science 和中国知网（CNKI）等数据库中收集了英文和中文文献。以甘草、提取、结构特征/鉴定、质量控制、代谢和药代动力学为关键词。
结果
总结了甘草化学分析的新开发分析方法，包括 LC/UV、2DLC、LC/MS、GC/MS 和质谱成像（MSI）。
结论
本综述提供了对甘草化学分析的全面总结。
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