Department of Chemistry, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Department of Chemistry, Yonsei University, 50, Yonsei-ro, Seodaemun-gu, Seoul, Republic of Korea.
Anal Chim Acta. 2022 Sep 15;1226:340287. doi: 10.1016/j.aca.2022.340287. Epub 2022 Aug 20.
Development of ultramicroelectrodes and nanoelectrodes opened interesting possibilities in the investigation electron transfer phenomena, including their application as probe electrodes in scanning electrochemical microscopy (SECM). Analytical prowess of SECM was often shadowed by long operation times required for analysis of a wide sample area. In this report, we developed a multi-channel nanoelectrode bundle for simultaneous electroanalysis of multiple orthogonal redox reactions in one bath. Four nanoelectrodes of diameters 100-400 nm were shown to be bundled in a 2 μm disk area. The nanoelectrode assembly was implemented as a tip electrode for multi-channel SECM, dramatically improving the time efficiency of SECM operations. The nanoelectrode bundle was also demonstrated as a stand-alone microprobe for electroanalytical investigations in small volumes such as ceramic confinements and biologically important compartments. The development reported in this work should benefit electrochemical analyses of various systems, especially those involving SECM and fine spatial control.
发展超微电极和纳米电极为研究电子转移现象提供了有趣的可能性，包括将其用作扫描电化学显微镜（SECM）中的探针电极。然而，SECM 的分析能力常常受到分析大面积样品所需的长时间操作的限制。在本报告中，我们开发了一种多通道纳米电极束，用于在一个浴中同时电分析多个正交的氧化还原反应。直径为 100-400nm 的四个纳米电极被捆绑在一个 2μm 的圆盘区域中。纳米电极组件被用作多通道 SECM 的尖端电极，极大地提高了 SECM 操作的时间效率。纳米电极束还可用作独立的微探针，用于在小体积（如陶瓷约束和生物重要隔室）中进行电分析研究。本工作中报道的发展应该有利于各种系统的电化学分析，特别是涉及 SECM 和精细空间控制的分析。
