Department of Neonatology and NICU, "San Carlo" Hospital, Potenza, Italy.
Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Ital J Pediatr. 2022 Sep 6;48(1):165. doi: 10.1186/s13052-022-01353-z.
Intraosseous (IO) access offers a fast and reliable route for administration of fluids and drugs when intravenous (IV) accesses like umbilical, peripheral, or peripherally inserted central lines fail in critically ill neonates. Several medications can be successfully administered via the IO route, however only limited information is available regarding IO administration of antiviral agents.We present the case of a 2-week-old neonate, admitted to the Neonatal Intensive Care Unit (NICU) due to suspected meningitis, who received acyclovir through IO infusion after the venous access was lost and a new one could not be established. No complications were reported within 12 months of follow up.This report highlights the feasibility of IO acyclovir infusion when IV accesses fail in a critically ill neonate.
当脐静脉、外周静脉或外周中心静脉置管等静脉通路在危重新生儿中失败时，骨内（IO）通路可提供快速可靠的输液和药物给药途径。有几种药物可以通过 IO 途径成功给药，但是关于抗病毒药物的 IO 给药，只有有限的信息。我们报告了一例 2 周大的新生儿，因疑似脑膜炎入住新生儿重症监护病房（NICU），在静脉通路丢失且无法建立新通路后，通过 IO 输注给予阿昔洛韦。在 12 个月的随访中，没有报告任何并发症。本报告强调了在危重新生儿 IV 通路失败时，IO 阿昔洛韦输注的可行性。
