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内镜辅助下显微手术切除累及海绵窦的右侧复发性梅克尔腔脑膜瘤

Endoscopic-Assisted Microsurgical Resection of Right Recurrent Meckel's Cave Meningioma Extended to Cavernous Sinus.

作者信息

Fava Arianna, di Russo Paolo, Giammattei Lorenzo, Froelich Sébastien

机构信息

Department of Neurosurgery, Lariboisiere Hospital, Paris, France.

Department of Neurosurgery, Lariboisiere Hospital, University of Paris Diderot, Paris, France.

出版信息

J Neurol Surg B Skull Base. 2021 May 11;83(Suppl 3):e632-e634. doi: 10.1055/s-0041-1725934. eCollection 2022 Aug.

Abstract

This study was aimed to present the complete removal of a large recurrent Meckel's cave meningioma.  This study is a case report.  The study was conducted at Department of Neurosurgery and Skull Base Laboratory at Lariboisiére Hospital, Paris.  A 53-year-old male was presented with a severe V1, V2, and V3 hypoesthesia and pain. He was operated 7 years ago for a right Meckel's cave meningioma with postoperative V1-V2 hypoesthesia. Magnetic resonance imaging (MRI) showed a large tumor recurrence extending into the cavernous sinus (CS), posterior fossa (PF), sphenoid sinus (SS), pterygopalatine (PPF), and infratemporal fossa (ITF; Fig. 1 ).  Radiological results and postoperative course were assessed for this study.  The previous right frontotemporal approach was used. The lateral wall of the orbit, the middle fossa floor and the anterior temporal base were drilled to expose the orbit, PPF, and ITF. Foramen ovale (FO), foramen rotondum (FR), and superior orbital fissure (SOF) were opened. The meningoorbital band was cut and the lateral wall of CS was elevated ( Fig. 2 ). The inferior orbital fissure was opened and tumor removed into the ITF, PPF, and orbit. After entering Meckel's cave from above, tumor was removed from PF. After microsurgical tumor removal, a 45-degree endoscope was used to remove tumor remnant and mucosa into SS. A watertight dural closure with pericranium was performed, reinforced with autologous fat and fibrin glue. Postoperative MRI showed complete tumor resection ( Fig. 1 ). The patient experienced a right-side keratitis that resolved within 10 days and a V3 hypoesthesia that improved at 2 months.  This surgical case shows how the anatomical knowledge is mandatory in skull base surgery and how the integration of microsurgical and endoscopic-assisted techniques allows to obtain optimal results. The link to the video can be found at: https://youtu.be/qxt_389AdWU .

摘要

本研究旨在介绍一例大型复发性梅克尔腔脑膜瘤的完整切除情况。

本研究为一例病例报告。

该研究在巴黎拉里博瓦西埃医院神经外科和颅底实验室进行。

一名53岁男性患者出现严重的V1、V2和V3感觉减退及疼痛。他7年前因右侧梅克尔腔脑膜瘤接受手术,术后出现V1 - V2感觉减退。磁共振成像(MRI)显示肿瘤复发且体积较大,延伸至海绵窦(CS)、后颅窝(PF)、蝶窦(SS)、翼腭窝(PPF)和颞下窝(ITF;图1)。

本研究评估了放射学结果及术后病程。

采用先前的右侧额颞入路。磨除眶外侧壁、中颅窝底和颞前基底,以暴露眼眶、PPF和ITF。打开卵圆孔(FO)、圆孔(FR)和眶上裂(SOF)。切断脑膜眶带,抬起CS外侧壁(图2)。打开眶下裂,将肿瘤切除至ITF、PPF和眼眶。从上方进入梅克尔腔后,从PF切除肿瘤。显微手术切除肿瘤后,使用45度内镜将肿瘤残余及黏膜切除至SS。用颅骨膜进行严密的硬膜缝合,并用自体脂肪和纤维蛋白胶加固。术后MRI显示肿瘤完全切除(图1)。患者出现右侧角膜炎,10天内消退,V3感觉减退在2个月时有所改善。

该手术病例展示了颅底手术中解剖学知识的必要性,以及显微手术和内镜辅助技术的结合如何实现最佳手术效果。视频链接:https://youtu.be/qxt_389AdWU

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