Sun M M, Zhou H F, Xu Q G, Wei S H
Ophthalmology Division of Chinese PLA General Hospital, Beijing 100039, China.
Zhonghua Yan Ke Za Zhi. 2022 Sep 11;58(9):719-721. doi: 10.3760/cma.j.cn112142-20211106-00522.
A 6-year-old girl had binocular vision loss with pain for one week. The patient presented with symptoms such as non-communication, language deterioration, dysphonia, and choking when drinking and eating during the course. The serum myelin oligodendrocyte glycoprotein antibody was positive. Both the serum and cerebrospinal fluid anti-N-methyl-D-aspartate receptor antibody were also positive. The diagnoses were myelin oligodendrocyte glycoprotein antibody positive optic neuritis and anti-N-methyl-D-aspartate receptor encephalitis. High-dose intravenous glucocorticoids were given. Recurrence was not observed during the 15-month clinical follow-up.
一名6岁女孩出现双眼视力丧失伴疼痛1周。患者在病程中出现不交流、语言退化、发音困难以及饮水和进食时呛咳等症状。血清髓鞘少突胶质细胞糖蛋白抗体呈阳性。血清和脑脊液抗N-甲基-D-天冬氨酸受体抗体也均为阳性。诊断为髓鞘少突胶质细胞糖蛋白抗体阳性视神经炎和抗N-甲基-D-天冬氨酸受体脑炎。给予大剂量静脉糖皮质激素治疗。15个月的临床随访期间未观察到复发。
