Curtin School of Allied Health, Faculty of Health Sciences, 1649Curtin University, Perth, WA, Australia.
Physiotherapy Department, 94920St John of God Midland Hospital, Perth, WA, Australia.
Chron Respir Dis. 2022 Jan-Dec;19:14799731221120429. doi: 10.1177/14799731221120429.
Compared to the general population, adults with chronic obstructive pulmonary disease (COPD) have an increased prevalence of osteoporosis. Despite the known risk factors and potential complications of compromised bone health in COPD, little is known about whether poor bone health is routinely suspected. We measured, in people with COPD, the prevalence of those who had one or more indicators suggestive of suspected poor bone health, and compared the characteristics of those with versus without these indicators.
Data were collected from adults with COPD presenting to three tertiary hospitals. Indicators of suspected poor bone health were defined as any of the following criteria: (i) self-reported problems with bone health, (ii) previous imaging for bone health, (iii) history of fragility fracture or, (iv) advised to use medication/supplements to optimise bone health. Characteristics compared between those with versus without indicators of suspected poor bone health comprised age, sex, body mass index (BMI), FEV% predicted and recruitment setting.
361 participants were included (age 70 ± 10, BMI 27.9 ± 7.8 kg/m, FEV% predicted 49 ± 20; 161 [45%] female). Indicators suggestive of suspected poor bone health were present in 53% (95% confidence interval [CI] 47-58) of the participants. The odds of this outcome increased with advancing age (odds ratio; OR [95% CI] 1.05 [1.03 to 1.08]) and being female (OR [95% CI] 3.4 [2.2 to 5.7]) .
In people with COPD, the odds of having indicators suggestive of suspected poor bone health increase with advancing age and in females. Further work is required to promote the importance of bone health in this population.
与一般人群相比，患有慢性阻塞性肺疾病（COPD）的成年人骨质疏松症的患病率增加。尽管已知 COPD 患者的骨骼健康存在潜在风险因素和并发症，但对于是否常规怀疑骨骼健康不良知之甚少。我们测量了 COPD 患者中存在一个或多个提示疑似骨骼健康不良的指标的患者比例，并比较了有这些指标和没有这些指标的患者的特征。
数据来自三家三级医院就诊的 COPD 成年人。疑似骨骼健康不良的指标定义为以下任何一项标准：（i）自述骨骼健康问题，（ii）以前进行过骨骼健康影像学检查，（iii）脆性骨折史，或（iv）建议使用药物/补充剂来优化骨骼健康。有和没有疑似骨骼健康不良指标的患者之间的特征比较包括年龄、性别、体重指数（BMI）、FEV%预测值和招募设置。
共纳入 361 名参与者（年龄 70 ± 10 岁，BMI 27.9 ± 7.8 kg/m，FEV%预测值 49 ± 20；161 [45%] 为女性）。有 53%（95%置信区间 [CI] 47-58）的参与者存在疑似骨骼健康不良的指标。该结果的可能性随着年龄的增长而增加（比值比；OR [95% CI] 1.05 [1.03 至 1.08]）和女性（OR [95% CI] 3.4 [2.2 至 5.7]）。
在 COPD 患者中，存在疑似骨骼健康不良指标的可能性随着年龄的增长和女性而增加。需要进一步努力提高该人群对骨骼健康的重视。
