Department of Psychology, The University of Texas, Austin, U.S.A.
Emerg Top Life Sci. 2022 Dec 9;6(5):445-455. doi: 10.1042/ETLS20220001.
Activation of the fear system is adaptive, and protects individuals from impending harm; yet, exacerbation of the fear system is at the source of anxiety-related disorders. Here, we briefly review the 'why' and 'how' of fear, with an emphasis on models that encapsulate the elegant complexity of rodents' behavioral responding in the face of impending harm, and its relevance to developing treatment interventions.
恐惧系统的激活是适应性的，可以保护个体免受即将到来的伤害；然而，恐惧系统的加剧是焦虑相关障碍的根源。在这里，我们简要回顾了恐惧的“为什么”和“如何”，重点介绍了那些能够捕捉到啮齿动物在面临即将到来的伤害时行为反应的优雅复杂性的模型，以及这些模型与开发治疗干预措施的相关性。
