Department of Psychiatry, Psychotherapy, Psychosomatics and Medical Psychology, University Hospital of Psychiatry II, Innsbruck Medical University, Innsbruck, Austria.
Institute of Mountain Emergency Medicine, Eurac Research, Bolzano, Italy.
High Alt Med Biol. 2022 Dec;23(4):338-344. doi: 10.1089/ham.2022.0014. Epub 2022 Sep 7.
Hüfner, Katharina, Fabio Caramazza, Evelyn R. Pircher Nöckler, Agnieszka E. Stawinoga, Paolo Fusar-Poli, Sanjeeb S. Bhandari, Buddha Basnyat, Monika Brodmann Maeder, Giacomo Strapazzon, Iztok Tomazin, Ken Zafren, Hermann Brugger, and Barbara Sperner-Unterweger. Association of pre-existing mental health conditions with acute mountain sickness at Everest Base Camp. 23:338-344, 2022. Mental health disorders are common, but limited data are available regarding the number of people with a past medical history of psychiatric diagnoses going to high altitude (HA). It is also unknown whether mental health conditions are associated with an increased risk of acute mountain sickness (AMS). We analyzed data from a previous study at Everest Base Camp. Participants self-reported their past medical history and history of substance use and had a brief history taken by a physician. AMS was assessed using the self-reported 2018 Lake Louise AMS Score. Eighty-five participants (66 men and 19 women, age 38 ± 9 years) were included. When questioned by a physician, 28 participants reported prior diagnoses or symptoms compatible with depression (23%), anxiety disorder (6%), post-traumatic stress disorder (1%), and psychosis/psychotic experiences (9%). The prevalence of psychiatric diagnoses in the past medical history was much lower in the self-reported data (2/85) compared to data obtained via physician assessment (28/85). Increased risks of AMS were associated with a past medical history of anxiety disorder (odds ratio [OR] 22.7; confidence interval [95% CI] 2.3-220.6; < 0.001), depression (OR 3.6; 95% CI 1.2-11.2; = 0.022), and recreational drug use ever (OR 7.3; 95% CI 1.5-35.5; = 0.006). Many people who travel to HA have a past medical history of mental health conditions. These individuals have an increased risk of scoring positive for AMS on the Lake Louise Score compared with people without a history of mental health conditions.
胡夫纳、卡塔琳娜、法比奥·卡拉马扎、伊芙琳·R·皮尔奇纳-诺克勒、阿格涅什卡·E·斯塔温加、保罗马尔扎波利、桑杰布·S·班达里、布达巴亚、莫妮卡·布罗德曼·马德、杰戈米·斯特拉帕佐恩、伊佐特·托马津、肯·扎夫伦、赫尔曼·布鲁格和芭芭拉·斯佩纳-翁特韦格。预先存在的心理健康状况与珠穆朗玛峰大本营急性高山病的关联。23:338-344，2022。心理健康障碍很常见，但关于有过去精神疾病诊断史的人前往高海拔地区（HA）的人数的数据有限。目前尚不清楚心理健康状况是否与急性高山病（AMS）的风险增加有关。我们分析了之前在珠穆朗玛峰大本营进行的一项研究的数据。参与者自我报告了他们过去的病史和药物使用史，并由医生进行了简要病史评估。AMS 使用自我报告的 2018 年路易斯湖 AMS 评分进行评估。 85 名参与者（66 名男性和 19 名女性，年龄 38±9 岁）被纳入研究。当被医生询问时，28 名参与者报告了过去的诊断或与抑郁（23%）、焦虑障碍（6%）、创伤后应激障碍（1%）和精神病/精神病体验（9%）相符的症状。与医生评估相比，自我报告数据中的精神科诊断患病率要低得多（2/85）（28/85）。过去有焦虑障碍（比值比 [OR] 22.7；95%置信区间 [95%CI] 2.3-220.6； < 0.001）、抑郁（OR 3.6；95% CI 1.2-11.2； = 0.022）和曾经使用娱乐性药物史（OR 7.3；95% CI 1.5-35.5； = 0.006）的人患 AMS 的风险增加。许多前往 HA 的人都有过去的心理健康状况史。与没有心理健康状况史的人相比，这些人在路易斯湖评分上获得 AMS 阳性评分的风险更高。
