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[紫外线对大鼠皮肤脂质过氧化作用及其调节的各种因素的影响]

[Effect of ultraviolet rays on lipid peroxidation and various factors of its regulation in the rat skin].

作者信息

Maĭsuradze V N, Platonov A G, Gudz' T I, Goncharenko E N, Kudriashov Iu B

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(5):31-5.

PMID:3607105
Abstract

The increase of the content of lipoperoxidation products, the decrease of antiradical activity of lipids and the activities of superoxide dismutase, glutathione peroxidase and glutathione reductase in the skin of rats have been found to be a result of ultraviolet (UV) radiation. The dose and time dependences of changes of these parameters have been obtained. It is suggested that intensification of lipid peroxidation in the skin of UV-radiated animals is correlated with the inhibition of the antiperoxide systems.

摘要

已发现大鼠皮肤中脂过氧化产物含量增加、脂质抗自由基活性以及超氧化物歧化酶、谷胱甘肽过氧化物酶和谷胱甘肽还原酶活性降低是紫外线(UV)辐射的结果。已获得这些参数变化的剂量和时间依赖性。有人提出,紫外线辐射动物皮肤中脂质过氧化的增强与抗过氧化物系统的抑制有关。

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1
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Nauchnye Doki Vyss Shkoly Biol Nauki. 1987(5):31-5.
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Involvement of lipid peroxidation and organic peroxides in UVA-induced matrix metalloproteinase-1 expression.脂质过氧化和有机过氧化物在紫外线A诱导的基质金属蛋白酶-1表达中的作用。
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