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在 T-CONCERN 研究中,实时数据显示急性缺血性卒中患者 1 年死亡率的预后。

Real-time data on the prognosis of acute ischemic stroke patients in the Tochigi Clinical ObservatioNal registry for 1-year mortality of aCute ischEmic stRoke patieNt (T-CONCERN) study.

机构信息

Division of Neurology, Department of Medicine, Jichi Medical University, Tochigi, Japan.

Department of Neurology, Shin-Oyama City Hospital, Tochigi, Japan.

出版信息

Neurol Sci. 2022 Dec;43(12):6855-6864. doi: 10.1007/s10072-022-06377-1. Epub 2022 Sep 7.

Abstract

BACKGROUND

It is important to gauge mortality in real time following an ischemic stroke. However, there is limited in-hospital and post-discharge clinical data that focuses on the real-time prognosis of acute ischemic strokes.

PURPOSE

To comprehensively analyze ischemic stroke mortality during a hospital stay and 1 year after the onset of a stroke.

MATERIALS AND METHODS

Initially, 1514 consecutive acute ischemic stroke patients were admitted to our facility within 7 days after the onset of a stroke. Of these, 1116 patients who were successfully surveyed 1 year after onset were finally analyzed. Baseline, physical, laboratory, and stroke clinical data were recorded and analyzed.

RESULTS

The proportion of deaths within 1 year was 14.5%, 4.9% without discharge was and 9.6% after discharge within 1 year. Cardioembolic ischemic strokes were responsible for nearly 50% of the deaths within 1 year while the remaining deaths were due to non-cardioembolic ischemic strokes. After 1 year, survival rate in the hospital decreased significantly, depending on whether the stroke was recurrent or if there was bleeding without a stroke.

CONCLUSIONS

Our study reveals the real-time survival data 1 year after the onset of a stroke, in-hospital and post-discharge mortality rates, and several issues associated with the treatment of acute ischemic strokes.

摘要

背景

实时评估缺血性卒中后的死亡率非常重要。然而,目前缺乏专注于急性缺血性卒中实时预后的有限院内和出院后临床数据。

目的

全面分析住院期间和卒中发病后 1 年的缺血性卒中死亡率。

材料和方法

最初,在卒中发病后 7 天内,我们机构收治了 1514 例连续的急性缺血性卒中患者。其中,最终对发病 1 年后成功进行调查的 1116 例患者进行了分析。记录和分析了基线、体格检查、实验室和卒中临床数据。

结果

1 年内的死亡率为 14.5%,无出院死亡率为 4.9%,1 年内出院后死亡率为 9.6%。心源性缺血性卒中导致近 50%的 1 年内死亡,其余死亡归因于非心源性缺血性卒中。1 年后,院内生存率显著下降,取决于卒中是否复发或是否有无卒中的出血。

结论

我们的研究揭示了卒中发病后 1 年的实时生存数据、院内和出院后死亡率以及与急性缺血性卒中治疗相关的几个问题。

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