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胃碰撞瘤，可能起源于异位胰腺。

Gastric collision tumour with probable ectopic pancreatic origin.

作者信息

Gonzáles Juan Francisco Olivos, Arroyo-Gárate Rodrigo, Estrella Miguel Angel Leon, Cerrillo Gustavo, Medinae Stefanie Campos

机构信息

Instituto Nacional de Enfermedades Neoplásicas, Surquillo 15038, Peru.

https://orcid.org/0000-0002-0559-0295.

出版信息

Ecancermedicalscience. 2022 Jun 13;16:1410. doi: 10.3332/ecancer.2022.1410. eCollection 2022.

DOI:10.3332/ecancer.2022.1410
PMID:36072234
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9377815/
Abstract

INTRODUCTION

Mixed histology tumours are rarely found in the stomach. Of these, collision tumours are mainly composed of adenocarcinomas and sarcomas or lymphomas. This is the seventh case reported in the literature of an acinar cell carcinoma arising from an ectopic pancreas located in the stomach and the first described within a collision tumour.

CLINICAL CASE

We present the case of a 58-year-old female patient diagnosed with gastric cancer who, after undergoing a total gastrectomy, presented with a pathology report describing findings compatible with gastric collision tumour with components of tubular adenocarcinoma and acinar cell carcinoma of probable pancreatic ectopic aetiology.

DISCUSSION

At the beginning of the 20th century, collision tumours were rarely described. Those located in the stomach are an infrequent pathology and are rarely diagnosed preoperatively. A collision tumour is composed of two independent neoplastic tissue with tumour areas separated in two different histological patterns and, in case of metastasis, this separation must also be clearly identified. There are different theories about its carcinogenesis and the debate regarding the ideal treatment is still ongoing.

CONCLUSION

This is the first report of a malignant gastric tumour with probable heterotopic pancreatic origin that collides with gastric adenocarcinoma.

摘要

引言

混合组织学类型的肿瘤在胃中很少见。其中，碰撞瘤主要由腺癌与肉瘤或淋巴瘤组成。这是文献报道的第七例起源于胃内异位胰腺的腺泡细胞癌，也是首次在碰撞瘤中描述的此类病例。

临床病例

我们报告一例58岁女性胃癌患者，在接受全胃切除术后，病理报告显示其结果符合胃碰撞瘤，伴有管状腺癌和可能由胰腺异位病因引起的腺泡细胞癌成分。

讨论

在20世纪初，碰撞瘤很少被描述。位于胃内的碰撞瘤是一种罕见的病理类型，术前很少被诊断出来。碰撞瘤由两种独立的肿瘤组织组成，肿瘤区域以两种不同的组织学模式分隔，在发生转移的情况下，这种分隔也必须清晰可辨。关于其致癌机制有不同的理论，关于理想治疗方法的争论仍在继续。

结论

这是首例可能起源于异位胰腺并与胃腺癌碰撞的恶性胃肿瘤报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/62dc1857f0dd/can-16-1410fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/bf0c6e516231/can-16-1410fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/3f8cea923ee7/can-16-1410fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/970fe8660fbd/can-16-1410fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/703de79b6cc5/can-16-1410fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/62dc1857f0dd/can-16-1410fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/bf0c6e516231/can-16-1410fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/3f8cea923ee7/can-16-1410fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/970fe8660fbd/can-16-1410fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/703de79b6cc5/can-16-1410fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04da/9377815/62dc1857f0dd/can-16-1410fig5.jpg

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