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接受根治性膀胱切除术治疗的原发性膀胱透明细胞癌女性患者的治疗结果：一例报告

Female patient's outcome of primary bladder clear cell carcinoma managed with radical cystectomy:A case report.

作者信息

Wang Xue-Bin, Jiang Bin

机构信息

Department of Urology Surgery, Dalian Municipal Friendship Hospital, Dalian, 116001, Liaoning Province, China.

出版信息

Urol Case Rep. 2022 Aug 26;45:102196. doi: 10.1016/j.eucr.2022.102196. eCollection 2022 Nov.

DOI:10.1016/j.eucr.2022.102196
PMID:36072282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9442332/
Abstract

Primary clear cell carcinoma of the urinary bladder is extremely rare reported only in case report or small case series. Due to its rarity, no consensus or recommendations are made on how to manage PCCUB and the pathogenesis of PCCUB is not clear. Based on histopathology and immunohistochemistry, a 58-year-old woman was diagnosed as PCCUB. The patient underwent radical cystectomy. Massive ascites and multiple lymph node metastasis occurred 6 months later. The diagnosis of PCCUB mainly depends on histopathology and immunohistochemistry. Although radical cystectomy is mainly applied for PCCUB treatment, the prognosis is poor in most cases.

摘要

膀胱原发性透明细胞癌极为罕见，仅在病例报告或小病例系列中有报道。由于其罕见性，对于如何治疗膀胱原发性透明细胞癌尚无共识或建议，且其发病机制尚不清楚。基于组织病理学和免疫组化检查，一名58岁女性被诊断为膀胱原发性透明细胞癌。该患者接受了根治性膀胱切除术。6个月后出现大量腹水和多发淋巴结转移。膀胱原发性透明细胞癌的诊断主要依靠组织病理学和免疫组化。虽然根治性膀胱切除术是治疗膀胱原发性透明细胞癌的主要方法，但大多数情况下预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/1c5328c55301/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/97a25b1bca0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/c68264239f4a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/1c5328c55301/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/97a25b1bca0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/c68264239f4a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ebb/9442332/1c5328c55301/gr3.jpg

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本文引用的文献

1
Clear cell carcinoma of the urinary bladder: a systematic review.膀胱透明细胞癌：系统评价。
Int Urol Nephrol. 2021 May;53(5):815-824. doi: 10.1007/s11255-020-02725-2. Epub 2021 Jan 18.
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Primary clear cell carcinoma of urinary bladder: A case report.膀胱原发性透明细胞癌：一例报告。
Urol Case Rep. 2017 Oct 19;16:41-43. doi: 10.1016/j.eucr.2017.10.008. eCollection 2018 Jan.
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Vesical clear cell adenocarcinoma arising from endometriosis: A mullerian tumor, indistinguishable from ovarian clear cell adenocarcinoma.
源于子宫内膜异位症的膀胱透明细胞腺癌：一种苗勒管肿瘤，与卵巢透明细胞腺癌难以区分。
Gynecol Oncol Rep. 2016 Aug 30;18:8-10. doi: 10.1016/j.gore.2016.08.005. eCollection 2016 Nov.
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Expression of PAX8 in nephrogenic adenoma and clear cell adenocarcinoma of the lower urinary tract: evidence of related histogenesis?PAX8在下尿路肾源性腺瘤和透明细胞腺癌中的表达：相关组织发生的证据？
Am J Surg Pathol. 2008 Sep;32(9):1380-7. doi: 10.1097/PAS.0b013e31816b1020.
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Histogenesis of clear cell adenocarcinoma in the urinary tract: evidence of urothelial origin.泌尿道透明细胞腺癌的组织发生：尿路上皮起源的证据。
Clin Cancer Res. 2008 Apr 1;14(7):1947-55. doi: 10.1158/1078-0432.CCR-07-4147.