Department of Hematology, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan 030013, Shanxi, China.
Contrast Media Mol Imaging. 2022 Aug 16;2022:6057017. doi: 10.1155/2022/6057017. eCollection 2022.
The aim of this study was to investigate the clinical value of positron emission tomography/computerized tomography scanning (PET/CT) in the evaluation of the effect of allogeneic hematopoietic stem cell transplantation in the treatment of T lymphoblastic lymphoma. 12 relevant research articles were collected through layer-by-layer screening in large databases such as Pubmed, Baidu Scholar, and China How Net, and analyzed and summarized using indicators such as progression-free survival (PFS), overall survival (OS), hazard ratio (HR), maximum standardized uptake value (SUV max), total metabolic tumor volume (TMTV), total lesion glycolysis (TLG), elevated lactate dehydrogenase (LDH), and 2-microglobulin (2-MG). The results showed that before treatment, F-FDG PET/CT baseline diagnosis could accurately stage the patients; during treatment, F-FDG PET/CT detection could provide effective treatment information; and after treatment, complications were found during F-FDG PET/CT detection. In summary, F-FDG PET/CT can monitor and evaluate treatment prognosis at baseline, middle, and late stages, and F-FDG PET/CT has become an indispensable and important examination technique in clinical work.
本研究旨在探讨正电子发射断层扫描/计算机断层扫描（PET/CT）在评估异基因造血干细胞移植治疗 T 淋巴母细胞淋巴瘤效果中的临床价值。通过逐层筛选 Pubmed、百度学术和中国知网等大型数据库，共收集了 12 篇相关研究文章，运用无进展生存（PFS）、总生存（OS）、风险比（HR）、最大标准化摄取值（SUVmax）、总代谢肿瘤体积（TMTV）、总病灶糖酵解（TLG）、乳酸脱氢酶（LDH）升高、β2-微球蛋白（2-MG）等指标进行分析和总结。结果表明，治疗前，F-FDG PET/CT 基线诊断能准确分期；治疗中，F-FDG PET/CT 检测能提供有效的治疗信息；治疗后，F-FDG PET/CT 检测发现并发症。总之，F-FDG PET/CT 能在基线、中期和晚期监测和评估治疗预后，F-FDG PET/CT 已成为临床工作中不可或缺的重要检查技术。
