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[从临床数据库到治疗方案的构想。以可手术乳腺癌为例]

[From a clinical data base to the conception of treatment protocols. Example in operable cancers of the breast].

作者信息

Durand M, Bonichon F, Avril A

出版信息

Bull Cancer. 1987;74(2):185-9.

PMID:3607301
Abstract

At Fondation Bergonié, a data base has been settled since ten years concerning all the patient who had been treated there for breast cancer. Collection of these data, compared with those reported in the medical literature, have allowed us to discuss orientations for clinical research, and to establish coherent treatment protocols fitting as much patients as possible. Eventually an interdisciplinary consensus was obtained on clinical trials to be performed, according to prognostic variables defined, and the foreseeable duration of patients inclusion and accrual.

摘要

在贝戈涅基金会,关于所有在那里接受乳腺癌治疗的患者的数据库已经建立了十年。将这些数据与医学文献中报道的数据进行比较,使我们能够讨论临床研究的方向,并制定适合尽可能多患者的连贯治疗方案。最终,根据定义的预后变量以及患者纳入和累积的可预见持续时间,就即将开展的临床试验达成了跨学科共识。

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1
[From a clinical data base to the conception of treatment protocols. Example in operable cancers of the breast].[从临床数据库到治疗方案的构想。以可手术乳腺癌为例]
Bull Cancer. 1987;74(2):185-9.
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Prognostic value of lymph node metastases after neoadjuvant chemotherapy for large-sized operable carcinoma of the breast.新辅助化疗后大尺寸可手术乳腺癌淋巴结转移的预后价值
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[Primary chemotherapy in operable breast carcinoma].[可手术乳腺癌的原发性化疗]
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Prognostic significance of residual breast disease and axillary node involvement for patients who had primary induction chemotherapy for advanced breast cancer.晚期乳腺癌患者接受初次诱导化疗后残余乳腺疾病及腋窝淋巴结受累情况的预后意义。
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[Metastatic cancer of the breast. Study of intensive induction of remission chemotherapy. Controlled clinical trial].[乳腺癌转移。缓解化疗强化诱导研究。对照临床试验]
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Expression of bcl-2 protein predicts efficacy of adjuvant treatments in operable node-positive breast cancer.bcl-2蛋白的表达可预测可手术的淋巴结阳性乳腺癌辅助治疗的疗效。
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