Aksu Tolga, Mutluer Ferit O, Tanboga Halil I, Gupta Dhiraj
Department of Cardiology, Yeditepe University Hospital, Istanbul, Turkey.
Department of Cardiology, Faculty of Medicine, Nisantası University, Istanbul, Turkey.
J Cardiovasc Electrophysiol. 2022 Nov;33(11):2394-2397. doi: 10.1111/jce.15672. Epub 2022 Sep 18.
We aimed to evaluate the incidence of acute pericarditis following cardioneuroablation (CNA) and to compare this with patients undergoing left atrial (LA) radiofrequency ablation for atrial fibrillation (AF).
This is a single-center prospective study. During the study period, CNA for vasovagal syncope was performed in 42 patients, pulmonary vein isolation (PVI) for paroxysmal AF in 46 patients, and posterior wall isolation (PWI) in addition to PVI for persistent AF in 22 patients. Pericarditis was reported by 18 (16.4%) patients overall: 1 (2.4%) patient in CNA group, 8 (17.4%) patients in PVI group, and 9 (40.9%) patients in PWI (p < .001). On univariable logistic regression analysis, CNA was associated with a lower risk of pericarditis (odds ratio 0.11, 95% confidence interval [CI] 0.01-0.97), while ablation of PWI plus PVI was associated with a higher risk of pericarditis compared with PVI (odds ratio 3.29, 95% CI 1.05-10.3).
This study shows that pericarditis is extremely uncommon following CNA and is significantly less frequent than following AF ablation. This difference is likely related to the much lower amount of LA ablation necessary in this group.
我们旨在评估心脏神经消融术（CNA）后急性心包炎的发生率，并将其与接受左心房（LA）射频消融治疗心房颤动（AF）的患者进行比较。
这是一项单中心前瞻性研究。在研究期间，42例患者接受了用于血管迷走性晕厥的CNA，46例患者接受了用于阵发性AF的肺静脉隔离（PVI），22例持续性AF患者除接受PVI外还接受了后壁隔离（PWI）。总体上有18例（16.4%）患者报告发生心包炎：CNA组1例（2.4%），PVI组8例（17.4%），PWI组9例（40.9%）（p<0.001）。单因素逻辑回归分析显示，CNA与心包炎风险较低相关（比值比0.11，95%置信区间[CI]0.01-0.97），而与PVI相比，PWI加PVI消融与心包炎风险较高相关（比值比3.29，95%CI 1.05-10.3）。
本研究表明，CNA后心包炎极为罕见，且明显少于AF消融术后。这种差异可能与该组所需的LA消融量少得多有关。
