Department of Radiotherapy, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland.
1st Radiation and Clinical Oncology Department, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Gliwice, Poland.
Pol J Pathol. 2022;73(2):176-179. doi: 10.5114/pjp.2022.119240.
We report a case of a 68-year-old patient with laryngeal chondrosarcoma, whose first symptoms were hoarseness and gradually increasing dyspnoea, but there was no sign of disease in clinical examination, which postponed the diagnosis. The patient underwent complete laryngectomy and adjuvant conformal radiotherapy with a total dose of 70 Gy. The pathological assessment confirmed advanced laryngeal chondrosarcoma originating from thyroid cartilage. Imaging studies and directoscopy were performed, and they did not reveal recurrence or metastases of the disease for 6 years. Distant metastatic spread in the liver and lungs was confirmed 7 years after diagnosis, which caused hepatic insufficiency and led to death.
我们报告了 1 例 68 岁患者患有喉软骨肉瘤，其首发症状为声音嘶哑和逐渐加重的呼吸困难，但临床检查无疾病迹象，这导致了诊断的延误。患者接受了全喉切除术和辅助适形放疗，总剂量为 70 Gy。病理评估证实高级喉软骨肉瘤源自甲状软骨。进行了影像学研究和直接镜检，6 年内未发现疾病复发或转移。诊断后 7 年，确认肝脏和肺部发生远处转移扩散，导致肝功能不全并最终导致死亡。
