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阑尾切除术中偶然发现的阑尾肿瘤:一家市级医院 19 年回顾性研究。

Incidental Appendiceal Tumors During Appendectomy: A Nineteen-Year Retrospective Review at a Municipal Hospital.

机构信息

Department of Surgery, Metropolitan Hospital Center, New York Medical College, New York, NY, USA.

Army Medical Department (AMEDD) Student Detachment, US Army Medical Center of Excellence, JBSA San Antonio, TX, USA.

出版信息

Am Surg. 2023 Dec;89(12):6251-6253. doi: 10.1177/00031348221114028. Epub 2022 Sep 8.

Abstract

Non-operative management of appendicitis (NOMA) has recently gained popularity, but a concern is that NOMA might miss appendiceal neoplasms. We conducted a retrospective review of 1694 appendectomies done for acute appendicitis at our institution between January 2001 and December 2019 to study the incidence and distribution of appendiceal tumors. We identified 24 appendiceal neoplasms (1.43%), including 9 Low Grade Appendiceal Mucinous Neoplasms (LAMNs), 6 neuroendocrine tumors (NETs), 6 mucoceles, and one each of adenocarcinoma, endometrioma, and neurofibroma. Tumor occurrence had two age peaks, with LAMNs prominent in the 5 and 6 decades of life and NETs in the 2 and 3 decades. All patients under age 40 had benign disease. Presence of appendicoliths was independent of the presence of neoplasms. All cases were managed per National Comprehensive Cancer Network (NCCN) guidelines, with twenty cases cured by appendectomy alone. Given these, we conclude that NOMA is safe for patients under 40.

摘要

非手术治疗阑尾炎(NOMA)最近越来越受欢迎,但人们担心 NOMA 可能会漏诊阑尾肿瘤。我们对 2001 年 1 月至 2019 年 12 月在我院行阑尾切除术治疗急性阑尾炎的 1694 例患者进行了回顾性研究,以研究阑尾肿瘤的发生率和分布。我们发现了 24 例阑尾肿瘤(1.43%),包括 9 例低级别阑尾黏液性肿瘤(LAMN)、6 例神经内分泌肿瘤(NET)、6 例黏液囊肿和 1 例腺癌、子宫内膜瘤和神经纤维瘤。肿瘤发生有两个年龄高峰,LAMN 在 50 岁和 60 岁多见,NET 在 20 岁和 30 岁多见。所有 40 岁以下的患者均为良性疾病。阑尾结石的存在与肿瘤的存在无关。所有病例均按照国家综合癌症网络(NCCN)指南进行治疗,20 例仅通过阑尾切除术治愈。基于这些结果,我们得出结论,对于 40 岁以下的患者,NOMA 是安全的。

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