Department of Anesthesiology, Division of Pain Medicine, University of Virginia, Charlottesville, VA, USA.
Pain Management Center, Fontaine Research Park, Third Floor, 545 Ray C Hunt Dr., Charlottesville, VA, 22908, USA.
Curr Pain Headache Rep. 2022 Oct;26(10):709-717. doi: 10.1007/s11916-022-01081-3. Epub 2022 Sep 8.
Pain medicine is rapidly expanding. The gap in treatment for patients with chronic pain in between traditional conservative therapy and major invasive surgery is closing. Neuromodulation is one therapeutic area that has continued to show promise for treatment of chronic pain. Our aim is to review updates in non-invasive neuromodulation (NIN) techniques as an adjunct for various chronic pain conditions.
Overall, the literature suggests that NIN techniques such as tCDS, TMS, TENS, tVNS, and HIFUS/LIFUS have utility in treating various types of chronic pain and have a promising future. There is a better understanding of the mechanistic basis for pain relief from NIN, as well as refinement in technology improving NIN therapy success. Future studies will need to focus on continuing to refine protocols for optimal benefit from NIN as well as implementing larger RCTs to improve the quality of data being generated in the field.
综述目的:疼痛医学正在迅速发展。在传统保守疗法和重大侵入性手术之间,慢性疼痛患者的治疗差距正在缩小。神经调节是一个持续为慢性疼痛治疗提供希望的治疗领域。我们的目的是回顾非侵入性神经调节(NIN)技术的最新进展,作为各种慢性疼痛疾病的辅助治疗手段。
最新发现:总体而言,文献表明,tCDS、TMS、TENS、tVNS 和 HIFUS/LIFUS 等 NIN 技术在治疗各种类型的慢性疼痛方面具有实用性,并且具有广阔的前景。人们对 NIN 缓解疼痛的机制基础有了更好的理解,同时也改进了技术,提高了 NIN 治疗的成功率。未来的研究需要专注于继续完善 NIN 的最佳方案,以及实施更大规模的 RCT,以提高该领域生成数据的质量。