Division of Cardiac Surgery, University of Pittsburgh Medical Center, Pittsburgh.
Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh.
Am J Cardiol. 2022 Nov 1;182:63-68. doi: 10.1016/j.amjcard.2022.07.026. Epub 2022 Sep 6.
Few studies have reported their experience in explantation of a transcatheter heart valve. We found 2,100 patients who underwent transcatheter aortic valve implantation (TAVI) from 2013 through 2021. Of 2,100, a total of 17 patients underwent surgical aortic valve replacement after TAVI, including surgical bailout. The mean age was 78.3 years. Co-morbidities were very frequent, including coronary artery disease (70.6%), atrial fibrillation (52.9%), cerebrovascular disease (47.1%), and pulmonary hypertension (41.2%). A history of cardiac surgery was observed in 6 patients (35.3%). The mean predicted risk of mortality at the time of TAVI was 7.7%. Surgical bailout was the most common indication of valve explantation (n = 8, 47.1%), followed by infective endocarditis (n = 4, 23.5%) and paravalvular leak (n = 2, 11.8%). The valve-in-valve TAVI was not feasible because of endocarditis, paravalvular leak, and history of valve-in-valve TAVI. Overall, 13 (76.5%) were performed urgently or emergently, and 10 (58.9%) required aortic root reconstruction. The mean cardiopulmonary bypass time was 158.5 minutes. In-hospital mortality was 41.2%. Transcatheter heart valve explantation continues to be rare; however, these data will continue to be informative as TAVI explantations will become more common with time.
很少有研究报告经导管心脏瓣膜取出术的经验。我们发现 2013 年至 2021 年期间共有 2100 例患者接受了经导管主动脉瓣植入术(TAVI)。在 2100 例患者中,共有 17 例患者在 TAVI 后接受了主动脉瓣置换手术,包括外科紧急情况。平均年龄为 78.3 岁。合并症非常常见,包括冠心病(70.6%)、心房颤动(52.9%)、脑血管疾病(47.1%)和肺动脉高压(41.2%)。6 例患者(35.3%)有心脏手术史。TAVI 时预测死亡率的平均风险为 7.7%。瓣膜取出的最常见指征是外科紧急情况(n=8,47.1%),其次是感染性心内膜炎(n=4,23.5%)和瓣周漏(n=2,11.8%)。由于心内膜炎、瓣周漏和经导管瓣膜置换术史,无法进行瓣中瓣 TAVI。总体而言,13 例(76.5%)紧急或紧急进行,10 例(58.9%)需要主动脉根部重建。体外循环时间平均为 158.5 分钟。院内死亡率为 41.2%。经导管心脏瓣膜取出术仍然很少见;然而,随着时间的推移,TAVI 取出术将变得更加常见,这些数据将继续提供信息。