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在尼日利亚北部卡诺的一家三级保健医疗机构中,死产的发生率及与社会人口统计学、生活环境和产妇健康的关系。

Incidence and sociodemographic, living environment and maternal health associations with stillbirth in a tertiary healthcare setting in Kano, Northern Nigeria.

机构信息

Centre for Trials Research, Cardiff University, Cardiff, UK.

Murtala Mohammed Specialist Hospital (MMSH), Kano, Nigeria.

出版信息

BMC Pregnancy Childbirth. 2022 Sep 8;22(1):692. doi: 10.1186/s12884-022-04971-x.

DOI:10.1186/s12884-022-04971-x
PMID:36076161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9454147/
Abstract

BACKGROUND

Almost two million stillbirths occur annually, most occurring in low- and middle-income countries. Nigeria is reported to have one of the highest stillbirth rates on the African continent. The aim was to identify sociodemographic, living environment, and health status factors associated with stillbirth and determine the associations between pregnancy and birth factors and stillbirth in the Murtala Mohammed Specialist Hospital, Kano, Nigeria.

METHODS

A three-month single-site prospective observational feasibility study. Demographic and clinical data were collected. We fitted bivariable and multivariable models for stillbirth (yes/no) and three-category livebirth/macerated stillbirth/non-macerated stillbirth outcomes to explore their association with demographic and clinical factors.

FINDINGS

1,998 neonates and 1,926 mothers were enrolled. Higher odds of stillbirth were associated with low-levels of maternal education, a further distance to travel to the hospital, living in a shack, maternal hypertension, previous stillbirth, birthing complications, increased duration of labour, antepartum haemorrhage, prolonged or obstructed labour, vaginal breech delivery, emergency caesarean-section, and signs of trauma to the neonate following birth.

INTERPRETATION

This work has obtained data on some factors influencing stillbirth. This in turn will facilitate the development of improved public health interventions to reduce preventable deaths and to progress maternal health within this site.

摘要

背景

每年约有两百万例死产,其中大多数发生在中低收入国家。据报道,尼日利亚的死产率在非洲大陆是最高的之一。本研究旨在确定与死产相关的社会人口学、生活环境和健康状况因素,并确定尼日利亚卡诺州默塔拉·穆罕默德专科医院妊娠和分娩因素与死产之间的关联。

方法

这是一项为期三个月的单站点前瞻性观察可行性研究。收集人口统计学和临床数据。我们拟合了两变量和多变量模型,用于死产(是/否)和三分类活产/木乃伊化死产/非木乃伊化死产结局,以探讨其与人口统计学和临床因素的关联。

结果

共纳入 1998 名新生儿和 1926 名母亲。母亲教育程度较低、到医院的距离较远、居住在棚屋、患有高血压、有过死产史、分娩并发症、产程延长、产前出血、产程延长或梗阻、阴道臀位分娩、紧急剖宫产以及新生儿出生后有创伤迹象与死产的发生几率更高相关。

结论

这项工作已经获得了一些影响死产的因素的数据。这反过来将有助于制定改进的公共卫生干预措施,以减少可预防的死亡,并在该地点推进母婴健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04df/9454147/37c9bc67ea1f/12884_2022_4971_Fig2a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04df/9454147/f35a053fa851/12884_2022_4971_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04df/9454147/37c9bc67ea1f/12884_2022_4971_Fig2a_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04df/9454147/f35a053fa851/12884_2022_4971_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04df/9454147/37c9bc67ea1f/12884_2022_4971_Fig2a_HTML.jpg

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BMC Pregnancy Childbirth. 2021 Dec 14;21(1):830. doi: 10.1186/s12884-021-04207-4.
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Understanding cause of stillbirth: a prospective observational multi-country study from sub-Saharan Africa.
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