Richards R R, Minas T, Johnston D W, Waddell J P
Can J Surg. 1987 Jul;30(4):245-8.
The Madreporic hip arthroplasty has provided encouraging clinical results. The surface of the prosthesis is unlike other uncemented prostheses since the rough surface is formed by multiple 1-mm diameter beads that are cast as an integral part of the prosthesis and increase its surface area four times. Seven Madreporic hip arthroplasties were implanted in adult male mongrel dogs. Specimens were harvested 5, 6, 9, 12, 20 and 52 weeks after insertion. One specimen became septic and loosened. The prosthesis was stabilized initially by friction fit between the prosthesis and the endosteal cortex of the proximal femur. Dense, uniformly organized, fibrous tissue surrounded the prosthesis at 5 weeks. The fibrous tissue appeared similar to Sharpey's fibres. Circumferential bone contact increased from 26% at 5 weeks to 60% at 52 weeks. Fluorescent labelling revealed active new bone formation within the interstices of the prosthesis without evidence of an intervening soft-tissue membrane. Firm mechanical anchorage of the Madreporic femoral prosthesis was demonstrated in this study.
多孔髋关节置换术已取得了令人鼓舞的临床效果。该假体的表面与其他非骨水泥型假体不同，其粗糙表面由多个直径为1毫米的珠子构成，这些珠子作为假体的一个整体部分铸造而成，使假体表面积增加了四倍。在成年雄性杂种犬体内植入了七个多孔髋关节置换假体。在植入后5、6、9、12、20和52周采集样本。有一个样本发生感染并松动。假体最初通过与股骨近端骨内膜皮质之间的摩擦配合实现稳定。5周时，假体周围有致密、组织均匀的纤维组织。该纤维组织看起来类似于夏佩氏纤维。周向骨接触率从5周时的26%增加到52周时的60%。荧光标记显示在假体间隙内有活跃的新骨形成，且没有中间软组织膜的迹象。本研究证明了多孔股骨假体具有牢固的机械锚固作用。
