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液体活检：临床应用与新兴技术之间不断变化的平衡

Liquid Biopsy, an Everchanging Balance between Clinical Utility and Emerging Technologies.

作者信息

Cucciniello Linda, Gerratana Lorenzo, Puglisi Fabio

机构信息

Department of Medicine (DAME), University of Udine, 33100 Udine, Italy.

Department of Medical Oncology, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, 33081 Aviano, Italy.

出版信息

Cancers (Basel). 2022 Sep 1;14(17):4277. doi: 10.3390/cancers14174277.

DOI:10.3390/cancers14174277
PMID:36077819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9454764/
Abstract

To date, tissue biopsy still represents the mainstay for tumor diagnosis and molecular characterization [...].

摘要

迄今为止，组织活检仍然是肿瘤诊断和分子特征分析的主要手段[...]。

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本文引用的文献

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Genomic Landscape of Advanced Solid Tumors in Circulating Tumor DNA and Correlation With Tissue Sequencing: A Single Institution's Experience.循环肿瘤 DNA 中晚期实体瘤的基因组图谱及其与组织测序的相关性：单机构经验。
JCO Precis Oncol. 2022 Jun;6:e2100289. doi: 10.1200/PO.21.00289.
2
Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance.四项血浆NGS检测与肿瘤的正交比较表明技术因素是检测不一致的主要来源。
JCO Precis Oncol. 2019 Dec;3:1-9. doi: 10.1200/PO.18.00191.
3
From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube.从采样到测序：一种液体活检分析前工作流程，以从单个样本管中最大化多层基因组信息
Cancers (Basel). 2021 Jun 15;13(12):3002. doi: 10.3390/cancers13123002.
4
Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer.转移性乳腺癌治疗监测中循环肿瘤细胞和循环肿瘤 DNA 的纵向动力学
JCO Precis Oncol. 2021 Jun 8;5:943-952. doi: 10.1200/PO.20.00345. eCollection 2021 Jun.
5
Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer.早期乳腺癌女性患者中经常检测到循环肿瘤细胞簇。
Cancers (Basel). 2021 May 13;13(10):2356. doi: 10.3390/cancers13102356.
6
Longitudinal Evaluation of PD-L1 Expression on Circulating Tumor Cells in Non-Small Cell Lung Cancer Patients Treated with Nivolumab.纳武单抗治疗的非小细胞肺癌患者循环肿瘤细胞上PD-L1表达的纵向评估
Cancers (Basel). 2021 May 11;13(10):2290. doi: 10.3390/cancers13102290.
7
Early Dissemination of Circulating Tumor Cells: Biological and Clinical Insights.循环肿瘤细胞的早期播散：生物学与临床见解
Front Oncol. 2021 May 7;11:672195. doi: 10.3389/fonc.2021.672195. eCollection 2021.
8
Detection of Genomically Aberrant Cells within Circulating Tumor Microemboli (CTMs) Isolated from Early-Stage Breast Cancer Patients.从早期乳腺癌患者中分离出的循环肿瘤微栓子（CTM）内基因组异常细胞的检测。
Cancers (Basel). 2021 Mar 19;13(6):1409. doi: 10.3390/cancers13061409.
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Cancers (Basel). 2021 Jan 31;13(3):535. doi: 10.3390/cancers13030535.