James H E, Tsueda K, Wright B, Young A B, McCloskey J
Acta Neurochir (Wien). 1978;43(3-4):275-80. doi: 10.1007/BF01587962.
The effect of positive end-expired pressure ventilation (PEEP) on mean systemic arterial pressure, mean pulmonary arterial pressure, mean pulmonary wedge pressure, mean intracranial pressure (ICP), and cerebral perfusion pressure (CPP), in a case of neurogenic pulmonary oedema (NPO) is presented. PEEP improved oxygenation, reduced, and finally stopped clinical pulmonary oedema. In this patient PEEP produced severe systemic hypotension. As a consequence of this, CPP was impaired.
本文介绍了呼气末正压通气(PEEP)对一例神经源性肺水肿(NPO)患者的平均体循环动脉压、平均肺动脉压、平均肺楔压、平均颅内压(ICP)和脑灌注压(CPP)的影响。PEEP改善了氧合,减轻并最终消除了临床肺水肿。但在该患者中,PEEP导致了严重的全身性低血压,进而损害了CPP。