佛波酯对动物细胞间连接通讯的抑制机制。
Mechanism of inhibition of junctional communication between animal cells by phorbol ester.
作者信息
Pitts J D, Burk R R
出版信息
Cell Tissue Kinet. 1987 Mar;20(2):145-51. doi: 10.1111/j.1365-2184.1987.tb01093.x.
Abstract
The tumour promotor 4 beta-phorbol 12-myristate 13-acetate (TPA) reduces the rate of junction formation between V79 Chinese hamster lung cells in culture but not between BHK21/13 Syrian hamster fibroblasts. TPA may act on all cells but only affect junction formation in those situations where the rate of junction formation is already low.
摘要
肿瘤促进剂4β-佛波醇12-肉豆蔻酸酯13-乙酸酯（TPA）可降低培养的V79中国仓鼠肺细胞之间的连接形成速率，但对BHK21/13叙利亚仓鼠成纤维细胞之间的连接形成速率没有影响。TPA可能作用于所有细胞，但仅在连接形成速率已经很低的情况下才影响连接形成。
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