Long Cheng-Yu, Lee Jennifer Po-Ning, Loo Zi-Xi, Liu Yi-Yin, Yeh Chang-Lin, Feng Chien-Wei, Lin Kun-Ling
Department of Obstetrics and Gynecology, Kaohsiung Medical Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Department of Obstetrics and Gynecology, Kaohsiung Municipal Siao-Gang Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
J Clin Med. 2022 Aug 24;11(17):4971. doi: 10.3390/jcm11174971.
Background: Our study aims to assess Pixel CO2 laser efficacy for female stress urinary incontinence (SUI). Methods: In the study, 25 women with SUI were included and scheduled for vaginal Pixel CO2 Laser (FemiLift™, Alma Lasers, Israel) treatment. All subjects had a baseline and 6-month post-treatment assessment that included three-dimensional perineal ultrasound and validated questionnaires. Results: Data showed that monthly three-session vaginal Pixel CO2 Laser treatment significantly improved SUI symptoms, as evidenced by validated questionnaires, including UDI-6, IIQ-7, ICIQ, and vaginal laxity questionnaire (p < 0.05). The Pixel CO2 Laser efficacy in vaginal treatment was 20/25 (80%), and the perineal sonography showed that laser treatment significantly decreased bladder neck mobility and middle urethral area (during resting and straining). Permanent adverse events were not found. Conclusions: The results of our study suggested that for the treatment of mild to moderate SUI symptoms, Pixel CO2 Laser is effective and safe; however, more studies and a longer follow-up should be conducted to confirm its efficacy and durability.
我们的研究旨在评估像素二氧化碳激光治疗女性压力性尿失禁（SUI）的疗效。方法：本研究纳入了25例压力性尿失禁女性患者，并安排她们接受阴道像素二氧化碳激光（FemiLift™，以色列阿尔玛激光公司）治疗。所有受试者在基线时和治疗后6个月进行评估，评估内容包括三维会阴超声检查和经过验证的问卷调查。结果：数据显示，每月进行三次的阴道像素二氧化碳激光治疗显著改善了压力性尿失禁症状，这在经过验证的问卷调查中得到了证实，包括UDI - 6、IIQ - 7、ICIQ以及阴道松弛度问卷（p < 0.05）。像素二氧化碳激光阴道治疗的有效率为20/25（80%），会阴超声检查显示激光治疗显著降低了膀胱颈活动度和中段尿道面积（在静息和用力时）。未发现永久性不良事件。结论：我们的研究结果表明，对于轻至中度压力性尿失禁症状的治疗，像素二氧化碳激光是有效且安全的；然而，需要进行更多研究和更长时间的随访来证实其疗效和持久性。
