Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.
Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China.
Molecules. 2022 Aug 29;27(17):5544. doi: 10.3390/molecules27175544.
This study describes the variation in residue behavior of fluopyram in soil, carrot root, and carrot leaf samples after the application of fluopyram (41.7% suspension, Bayer) by foliar spray or root irrigation at the standard of 250.00 g active ingredient per hectare (a.i./ha) and double-dose treatment (500.00 g a.i./ha). Fluopyram and its metabolite fluopyram-benzamide were extracted and cleaned up using the QuEChERS method and subsequently quantified with LC-QQQ-MS/MS. The LOD and LOQ of the developed method were in the range of 0.05-2.65 ug/kg and 0.16-8.82 ug/kg, respectively. After root irrigation, the final residues detected in edible parts were 0.60 and 1.80 mg/kg, respectively, when 250.00 and 500.00 g a.i./ha were applied, which is much higher than the maximum residue limit in China (0.40 mg/kg). In contrast, after spray application, most of the fluopyram dissipated from the surface of carrot leaves, and the final residues in carrot roots were both only 0.05 mg/kg. Dietary risk assessments revealed a 23-40% risk quotient for the root irrigation method, which was higher than that for the foliar spray method (8-14%). This is the first report comparing the residue behavior of fluopyram applied by root irrigation and foliar spray. This study demonstrates the difference in risk associated with the two application methods and can serve as a reference for the safe application of fluopyram.
本研究描述了氟吡呋喃胺（41.7%悬浮剂，拜耳）以标准用量 250.00 克有效成分/公顷（a.i./ha）和加倍剂量（500.00 g a.i./ha）进行叶面喷雾或根部灌溉后，在土壤、胡萝卜根和胡萝卜叶样本中的残留行为变化。使用 QuEChERS 方法提取和净化氟吡呋喃胺及其代谢物氟吡呋喃胺-苯甲酰胺，然后使用 LC-QQQ-MS/MS 进行定量。所建立方法的 LOD 和 LOQ 分别在 0.05-2.65 ug/kg 和 0.16-8.82 ug/kg 范围内。根部灌溉后，当使用 250.00 和 500.00 g a.i./ha 时，可食部分中检测到的最终残留量分别为 0.60 和 1.80 mg/kg，远高于中国的最大残留限量（0.40 mg/kg）。相比之下，喷雾施用后，大部分氟吡呋喃胺从胡萝卜叶表面消散，胡萝卜根中的最终残留量均仅为 0.05 mg/kg。膳食风险评估显示，根部灌溉法的风险商数为 23-40%，高于叶面喷雾法（8-14%）。这是首次比较根部灌溉和叶面喷雾施用氟吡呋喃胺的残留行为。本研究表明了两种施药方法所带来的风险差异，可为氟吡呋喃胺的安全施用提供参考。
