Gebremichael Lemlem G, Beleigoli Alline, Champion Stephanie, Nesbitt Katie, Bulto Lemma N, Pinero de Plaza Maria Alejandra, Pearson Vincent, Noonan Sara, Hendriks Jeroen M, Hines Sonia, Clark Robyn A
Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia.
Mparntwe Centre for Evidence in Health, Flinders University: A JBI Centre of Excellence, Alice Springs, NT, Australia.
JBI Evid Synth. 2022 Dec 1;20(12):2986-2994. doi: 10.11124/JBIES-21-00457.
The objective of this review is to measure the effectiveness of cardiac rehabilitation programs versus standard care on medication adherence in patients with cardiovascular disease.
Poor adherence to long-term medications increases the risk of morbidity and mortality, and decreases quality of life in patients with cardiovascular diseases. Several strategies have been trialed to improve medication adherence, one of which is cardiac rehabilitation programs. Although evidence has indicated that such programs increase medication adherence, the extent of their effectiveness and translation into clinical practice is not well documented. Our systematic review will collect and analyze the available evidence for clinical practice implementation.
The search will aim to locate randomized controlled trials. Where randomized controlled trials are not available, quasi-experimental studies, case-control studies, observational studies, and other study designs will be included. Studies that measure effectiveness of cardiac rehabilitation programs compared with standard care on medication adherence in cardiovascular disease patients will be included.
Databases, including MEDLINE (Ovid), Emcare (Ovid), Embase (Ovid), Cochrane CENTRAL, Scopus, CINAHL (EBSCO), and unpublished sources will be searched. Articles in English and non-English-language articles with an English abstract, published from database inception to the present, will be included. Articles will be screened and reviewed by 2 independent reviewers for inclusion. Critical appraisal tools will be applied to the included studies. Data will be extracted using the appropriate extraction tools and synthesized for the objectives of the study.
PROSPERO CRD42021284705.
本综述的目的是衡量心脏康复计划与标准护理相比，对心血管疾病患者药物依从性的有效性。
长期药物治疗依从性差会增加发病率和死亡率风险，并降低心血管疾病患者的生活质量。已经尝试了多种策略来提高药物依从性，其中之一是心脏康复计划。尽管有证据表明此类计划可提高药物依从性，但其有效性程度以及在临床实践中的转化情况尚无充分记录。我们的系统综述将收集和分析可用于临床实践实施的证据。
检索旨在找到随机对照试验。若没有随机对照试验，则将纳入准实验研究、病例对照研究、观察性研究及其他研究设计。将纳入测量心脏康复计划与标准护理相比对心血管疾病患者药物依从性有效性的研究。
将检索包括MEDLINE（Ovid）、Emcare（Ovid）、Embase（Ovid）、Cochrane CENTRAL、Scopus、CINAHL（EBSCO）在内的数据库以及未发表的资料来源。将纳入自数据库创建至今发表的英文文章以及带有英文摘要的非英文文章。文章将由2名独立审稿人进行筛选和评审以确定是否纳入。将对纳入研究应用批判性评价工具。将使用适当的提取工具提取数据，并为研究目的进行综合分析。
PROSPERO CRD42021284705。
