Balderston R A, Hiller W D, Iannotti J P, Pickens G T, Booth R E, Gluckman S J, Buckley R M, Rothman R H
Clin Orthop Relat Res. 1987 Aug(221):231-7.
Forty-three patients, 23 with definite infection and 20 with probable infections before total hip arthroplasty (THA), were compared to 41 matched uninfected patients. The 43 infected patients were treated by 45 operative procedures: eight Girdlestone resections, 12 revisions of total hips, and 25 conversions from infected nontotal hip surgery to total hip arthroplasties. (Two revision THAs were converted to Girdlestones). The average follow-up period was 38.8 months, with a range of six-118 months. The statistically significant negative prognosticators were gross sepsis at surgery, number of previous operations, and elevated erythrocyte sedimentation rate (ESR). The type of infecting organism did not affect the outcome. The prosthesis survival rate for total hip arthroplasties revised for sepsis was 83%. The prosthesis survival rate for other infected hips treated by total hip arthroplasty was 100%. All groups except Girdlestone resections improved postoperatively. While Girdlestone resection offered acceptable pain relief, total hip arthroplasty provided unequivocally superior function (p = 0.0001).
43例患者，其中23例在全髋关节置换术（THA）前确诊感染，20例可能感染，与41例匹配的未感染患者进行比较。43例感染患者接受了45次手术治疗：8例Girdlestone切除术，12例全髋关节翻修术，以及25例从感染性非全髋关节手术转为全髋关节置换术。（2例翻修THA转为Girdlestone手术）。平均随访期为38.8个月，范围为6 - 118个月。具有统计学意义的负面预后因素为手术时的严重脓毒症、既往手术次数和红细胞沉降率（ESR）升高。感染病原体的类型不影响预后。因脓毒症翻修的全髋关节置换术的假体生存率为83%。通过全髋关节置换术治疗的其他感染髋关节的假体生存率为100%。除Girdlestone切除术组外，所有组术后均有改善。虽然Girdlestone切除术能提供可接受的疼痛缓解，但全髋关节置换术提供了明显更好的功能（p = 0.0001）。
