单峰驼中作为代谢物和节能机制的嘌呤补救：鸟嘌呤的回收
Purine salvage as metabolite and energy saving mechanism in Camelus dromedarius: the recovery of guanine.
作者信息
Mura U, Osman A M, Mohamed A S, Di Martino D, Ipata P L
出版信息
Comp Biochem Physiol B. 1987;87(1):157-60. doi: 10.1016/0305-0491(87)90483-4.
PMID:3608430
Abstract
The preservation of purine ring as purine bases appears to be a common feature of camel liver. Hepatic guanine appears to be actively converted into GMP in the camel rather than further degraded. The limiting step of guanine degradation appears to be the lack of hepatic guanase activity. Higher purine bases over uric acid ratios were found in camel urine with respect to those of zebu.
摘要
嘌呤环以嘌呤碱基形式保存似乎是骆驼肝脏的一个共同特征。在骆驼体内，肝脏中的鸟嘌呤似乎会被积极转化为鸟苷酸，而不是进一步降解。鸟嘌呤降解的限速步骤似乎是肝脏中缺乏鸟苷酶活性。与瘤牛相比，骆驼尿液中嘌呤碱基与尿酸的比例更高。
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