Division of Clinical Geriatrics, Center for Alzheimer's Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Karolinska University Hospital, Karolinska Vägen 37 A, QA32, Stockholm, Solna 171 64, Sweden; Ageing Epidemiology Research Unit (AGE), School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom.
Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet/Stockholm University, Stockholm, Sweden.
Arch Gerontol Geriatr. 2023 Jan;104:104802. doi: 10.1016/j.archger.2022.104802. Epub 2022 Aug 31.
Psychosocial working conditions are associated with cognitive and physical impairments. The aim of this study was to investigate the associations between mid-late life psychosocial working conditions and the combination of physical and cognitive impairment among older adults, and the potential sex differences in these associations.
Data were derived from two Swedish nationally representative surveys (n = 839; follow-up: 20-24 years). Multinomial and binary logistic regressions assessed the associations between work stressors (job demand-control model), and a combination of cognitive and physical impairment.
Low control jobs were significantly associated with higher odds of cognitive (OR: 1.41, CI: 1.15-1.72) and physical impairment (OR: 1.23, CI: 1.02-1.47), and cognitive and physical impairment combined (OR: 1.50, CI: 1.19-1.89). Passive jobs (low control, low demand) were associated with higher odds of cognitive impairment (OR: 1.57, CI: 1.12-2.20), and combined cognitive and physical impairment (OR: 1.59, CI: 1.07-2.36). Active jobs (high control, high demand) were associated with lower odds of cognitive impairment (OR: 0.48, CI: 0.29-0.80). Sex-stratified analyses showed stronger associations among men; passive jobs were associated with both cognitive (OR: 2.18, CI: 1.31-3.63) and physical impairment (OR: 1.78, CI: 1.13-2.81), while low strain jobs were associated with less physical impairment (OR: 0.55, CI: 0.33-0.89). No significant associations between work stressors and impairment were found for women.
These results highlight the importance of psychosocial working conditions for late-life physical and cognitive impairment, especially among men. Jobs characterised by low control and low demands are associated with higher risk for impairments.
心理社会工作条件与认知和身体损伤有关。本研究旨在调查中老年心理社会工作条件与老年人身体和认知损伤综合的关系,并探讨这些关联中的潜在性别差异。
数据来自两次瑞典全国代表性调查(n=839;随访:20-24 年)。使用多项和二元逻辑回归评估工作压力源(工作需求-控制模型)与认知和身体损伤综合的关联。
低控制工作与认知损伤(OR:1.41,CI:1.15-1.72)和身体损伤(OR:1.23,CI:1.02-1.47)以及认知和身体损伤综合的发生风险显著增加相关。被动工作(低控制、低需求)与认知损伤(OR:1.57,CI:1.12-2.20)和认知与身体损伤综合的发生风险显著增加相关(OR:1.59,CI:1.07-2.36)。积极工作(高控制、高需求)与认知损伤(OR:0.48,CI:0.29-0.80)的发生风险显著降低相关。按性别分层分析显示,男性关联更强;被动工作与认知损伤(OR:2.18,CI:1.31-3.63)和身体损伤(OR:1.78,CI:1.13-2.81)均显著相关,而低压力工作与身体损伤减少显著相关(OR:0.55,CI:0.33-0.89)。对于女性,工作压力源与损伤之间无显著关联。
这些结果突出了心理社会工作条件对晚年身体和认知损伤的重要性,尤其是对男性。低控制和低需求的工作与损伤风险增加相关。