Department of Internal Medicine, Evangelismos General Hospital, 45-47 Ipsilantou Str, 10676, Athens, Greece.
Department of Internal Medicine, Evangelismos General Hospital, 45-47 Ipsilantou Str, 10676, Athens, Greece.
Anaerobe. 2022 Oct;77:102637. doi: 10.1016/j.anaerobe.2022.102637. Epub 2022 Sep 6.
Acute pyogenic vertebral osteomyelitis is mainly attributed to haematogenous spread of aerobic bacteria, while anaerobic osteomyelitis results from contiguous spread of polymicrobial infections through breaks in the gut mucosal barrier and involves the vertebral bodies in only about 2%-5%. Herein, we report two cases of vertebral osteomyelitis due to Bacteroides fragilis. It is noteworthy that cases of vertebral osteomyelitis due to Bacteroides fragilis have been attributed to the extension of intra-abdominal or pelvic floor infections. However, in the two cases described, there was no history of a previous medical intervention nor an intestinal or pelvic floor infection. Early recognition of the aetiological agent that causes vertebral osteomyelitis may lead to the timely treatment and therefore, may deter any neurosurgical/orthopaedic interventions.
急性化脓性脊椎骨骨髓炎主要归因于需氧菌的血源性传播，而厌氧性骨髓炎则是由于肠道黏膜屏障破裂导致多种微生物的继发感染，累及脊椎骨的比例约为 2%-5%。在此，我们报告两例脆弱拟杆菌引起的脊椎骨骨髓炎。值得注意的是，脆弱拟杆菌引起的脊椎骨骨髓炎归因于腹腔或骨盆底感染的扩散。然而，在描述的两例中，没有既往医疗干预或肠道或骨盆底感染的病史。早期识别引起脊椎骨骨髓炎的病原体可能有助于及时治疗，从而避免神经外科/骨科干预。
