Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:4123-4126. doi: 10.1109/EMBC48229.2022.9871144.
Nerve cuff electrodes are commonly used for neural stimulation and recording applications. Usually, these electrodes are composed of a limited set of metal rings, disposed around the nerve. Although widely used, this technology may be insufficient to record and stimulate in a more selective manner. Higher resolution electrodes, usually composed of a matrix of independent contact points, have been proposed in this sense. These electrodes allow for the exploration of a wide variety of bipolar or multipolar setups, for selective recording and stimulation. In this study, we propose a method to optimally select such multipolar setups and to quantitatively evaluate the performance of a multi-contact neural organic electrode (OE) in recording burst discharges from the rat's phrenic nerve. A 16-channel OE was wrapped around the phrenic nerve (studied electrode) and a suction electrode was applied to the cut-end of the same nerve (gold standard electrode). Analysis of all possible combinations of bipoles and tripoles from the OE were carried out to assess the improvement in the recording performance, measured as the signal-to-noise ratio, compared to the gold standard. The results showed that the bipolar and tripolar configuration significantly increased the overall recording performance. Such configurations are therefore essential to improve nerve burst detection.
神经袖电极常用于神经刺激和记录应用。通常，这些电极由一组有限的金属环组成，环绕在神经周围。尽管这种技术被广泛应用，但它可能不足以更具选择性地进行记录和刺激。为此，已经提出了更高分辨率的电极，通常由独立触点的矩阵组成。这些电极允许探索各种双极或多极设置，以进行选择性记录和刺激。在这项研究中，我们提出了一种方法来优化选择这种多极设置，并定量评估多接触神经有机电极 (OE) 在记录大鼠膈神经爆发放电方面的性能。一个 16 通道的 OE 被包裹在膈神经周围（研究电极），一个吸力电极被应用于同一神经的末端（金标准电极）。对 OE 中的所有双极和三极组合进行了分析，以评估与金标准相比，记录性能（以信噪比衡量）的提高。结果表明，双极和三极配置显著提高了整体记录性能。因此，这些配置对于改善神经爆发检测至关重要。
