Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:4978-4981. doi: 10.1109/EMBC48229.2022.9871318.
The analysis of the fetal electrocardiogram (ECG) requires to remove the mother ECG (mECG) from the abdominal ECG signals. Template subtraction is a method that consists in modeling and removing the mECG's mean period i.e. the signal waveform defined as the Euclidean mean of all periods. This mean period is then subtracted to all periods to extract the fetal ECG (fECG). Such a method is not accurate because each mECG's period is not correctly aligned with the mean period. We propose to take account of the diffeomorphism of each period to improve the precision of the model and remove the mECG more efficiently. The soft-dynamic time warping (DTW) algorithm is used to compute the mean mECG period and the alignment between the mean period and all periods. Our approach is compared to a classic template subtraction on synthetic and real databases. Results show that considering the dynamic time warping allows a better removal of the mECG. Clinical relevance - The template subtraction is modified in this paper to consider the time warping for each mother ECG's period in order to improve the fetal ECG extraction from the abdominal ECG.
胎儿心电图(ECG)的分析需要从腹部 ECG 信号中去除母亲心电图(mECG)。模板减法是一种通过建模和去除 mECG 的平均周期(即定义为所有周期的欧几里得平均值的信号波形)来去除 mECG 的方法。然后,将这个平均周期从所有周期中减去,以提取胎儿心电图(fECG)。这种方法并不准确,因为每个 mECG 的周期与平均周期并不完全对齐。我们建议考虑每个周期的微分同胚性,以提高模型的精度并更有效地去除 mECG。使用软动态时间规整(DTW)算法来计算平均 mECG 周期和平均周期与所有周期之间的对齐。我们的方法与合成和真实数据库上的经典模板减法进行了比较。结果表明,考虑动态时间规整可以更好地去除 mECG。临床相关性-本文修改了模板减法,以考虑每个母亲心电图周期的时间规整,以便从腹部 ECG 中更好地提取胎儿心电图。