基于递归图的缺血性和扩张型心肌病患者分类。
Recurrence Plot-based Classification of Ischemic and Dilated Cardiomyopathy Patients.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2022 Jul;2022:1394-1397. doi: 10.1109/EMBC48229.2022.9871298.
A large portion of the elderly population are affected by cardiovascular diseases. The early prognosis of cardiomyopathies is still a challenge. The aim of this study was to classify cardiomyopathy patients by their etiology in function of significant indexes extracted from the characterization of the recurrence plot of the systems involved. Thirty-nine cardiomyopathy patients (CMP) classified as ischemic (ICM - 24 patients) and dilated (DCM-15 patients) were considered. In addition, thirty-nine control subjects (CON) were used as reference. The beat-to-beat (BBI) time series, from the electrocardiographic signal, the systolic (SBP), and diastolic (DBP) time series, from the blood pressure signal, and the respiratory time (FLW) from the respiratory flow signal, were extracted. The recurrence plot from each signal considered were calculated and characterized by a total of 12 indexes. The best classifiers were used to build support vector machine models. The optimal model to classify ICM versus DCM patients achieved 92.3% accuracy, 95.8% sensitivity, and 86.6% specificity. When comparing CMP patients and CON subjects, the best model achieved 85.8% accuracy, 92.3% sensitivity, and 80.1% specificity. Our results suggest a more deterministic behavior in DCM patients. Clinical Relevance - This study explores the recurrence plot for the classification of ICM and DCM patients.
很大一部分老年人都受到心血管疾病的影响。心肌病的早期预后仍然是一个挑战。本研究的目的是通过对涉及的系统的递归图特征提取的显著指标进行分类,来对心肌病患者进行病因分类。考虑了 39 名心肌病患者(CMP),分为缺血性(ICM-24 名患者)和扩张型(DCM-15 名患者)。此外,还使用了 39 名对照受试者(CON)作为参考。从心电图信号中提取了逐拍(BBI)时间序列、从血压信号中提取了收缩压(SBP)和舒张压(DBP)时间序列、从呼吸流量信号中提取了呼吸时间(FLW)。计算了每个信号的递归图,并通过 12 个指标对其进行了特征描述。使用最佳分类器构建支持向量机模型。最佳模型可用于对 ICM 与 DCM 患者进行分类,其准确率为 92.3%,灵敏度为 95.8%,特异性为 86.6%。当比较 CMP 患者和 CON 受试者时,最佳模型的准确率为 85.8%,灵敏度为 92.3%,特异性为 80.1%。我们的研究结果表明 DCM 患者的行为更为确定。临床意义——本研究探索了递归图在 ICM 和 DCM 患者分类中的应用。