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皮肤灌注压测量在糖尿病足伤口中的临床应用:一项观察性研究。

Clinical utility of skin perfusion pressure measurement in diabetic foot wounds: An observational study.

机构信息

Department of Orthopaedic Surgery, Korea University Guro Hospital, Seoul, Republic of Korea.

Department of Orthopaedic Surgery, Soonchunhyang University, Cheonan Hospital, CheonanRepublic of Korea.

出版信息

Medicine (Baltimore). 2022 Sep 9;101(36):e30454. doi: 10.1097/MD.0000000000030454.

Abstract

The degree of blood vessel stenosis significantly influences diabetic foot treatment. This study aimed to investigate the association between computed tomography angiography (CTA) stenosis and skin perfusion pressure (SPP), which are noninvasive vascular assessments used to evaluate diabetic foot wounds. Forty patients who reported diabetic foot wounds between November 2016 and December 2017 were included in the study. SPPand CTA were performed to evaluate the blood flow, and the rate of decrease in wound size was measured for the wounds corresponding to Meggitt-Wagner grade 1 at the first evaluation and 4-week intervals. The P value of the association between the degree of CTA stenosis and the SPP value was 0.915, and the P value of the association between CTA stenosis and decreasing rate of wound size was .235. There was no statistically significant association between SPP and the decreasing rate of wound size according to the degree of CTA stenosis. The association between SPP value and the decreasing rate of wound size was statistically significant (P < .05). The decreasing rate in diabetic foot wound size was significantly associated with SPP but not with CTA stenosis.

摘要

血管狭窄程度对糖尿病足的治疗有重要影响。本研究旨在探讨计算机断层血管造影(CTA)狭窄与皮肤灌注压(SPP)之间的关系,这两种非侵入性血管评估方法用于评估糖尿病足伤口。本研究纳入了 2016 年 11 月至 2017 年 12 月间报告有糖尿病足伤口的 40 名患者。对患者进行 SPP 和 CTA 以评估血流情况,并在首次评估和 4 周间隔时测量与 Meggitt-Wagner 1 级相对应的伤口的大小减小率。CTA 狭窄程度与 SPP 值之间的关联的 P 值为 0.915,而 CTA 狭窄程度与伤口大小减小率之间的关联的 P 值为.235。根据 CTA 狭窄程度,SPP 与伤口大小减小率之间没有统计学显著关联。SPP 值与伤口大小减小率之间的关联具有统计学意义(P <.05)。糖尿病足伤口大小的减小率与 SPP 显著相关,而与 CTA 狭窄无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/10980428/41a1fe2494a5/medi-101-e30454-g001.jpg

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