Solar Cell Applications Research Lab, Department of Physics, Government College University Lahore, 54000, Pakistan.
Department of Clinical Sciences, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of Agriculture, Multan 66000, Pakistan.
Int J Biol Macromol. 2022 Nov 30;221:496-507. doi: 10.1016/j.ijbiomac.2022.09.034. Epub 2022 Sep 7.
A chemical co-precipitation route was used to synthesize novel strontium oxide (SrO), SrO-starch composite and various tellurium (Te) concentrations were incorporated in SrO-starch composite. This study aims to enhance the catalytic activities and bactericidal behavior of SrO, SrO-starch composite with different percentage concentrations of Te doping and a fixed amount of starch nanoparticles. XRD affirmed that the dopant contribution was investigated to improve crystallinity. Surface morphological characteristics and elemental composition evaluation were determined using an FE-SEM and EDS exhibit a doping concentration of an element in the synthesized products. The configuration of Sr-O-Sr bonds and molecular vibrations has been indicated by FTIR spectra. In addition, dye degradation of prepared samples was investigated through catalytic activity (CA) in the existence of NaBH act as a reduction representative. The Te-doped SrO-starch composite indicates superior catalytic activity and shows a degradation of Methylene blue dye (91.4 %) in an acidic medium. The synthesis nanocatalyst demonstrated impressive antibacterial activity against Staphylococcus aureus (S. aureus) at high and low concentrations exhibiting zones of inhibition 9.30 mm as compared to ciprofloxacin. Furthermore, molecular docking studies of synthesized nanocomposites were performed against selected enzyme targets, i.e., β-lactamase and DNA Gyrase.
采用化学共沉淀法合成了新型氧化锶(SrO)、氧化锶-淀粉复合物,并在 SrO-淀粉复合物中掺入了不同浓度的碲(Te)。本研究旨在提高 SrO、SrO-淀粉复合物的催化活性和杀菌性能,采用不同百分比浓度的 Te 掺杂和固定量的淀粉纳米粒子。XRD 证实了掺杂的贡献,以提高结晶度。FE-SEM 和 EDS 用于表面形貌特征和元素组成评估,显示出合成产物中元素的掺杂浓度。FTIR 光谱表明 Sr-O-Sr 键的结构和分子振动。此外,通过 NaBH 的存在作为还原代表,研究了制备样品的催化活性(CA)对染料降解的影响。Te 掺杂 SrO-淀粉复合物表现出优异的催化活性,在酸性介质中对亚甲蓝染料的降解率达到 91.4%。合成纳米催化剂对金黄色葡萄球菌(S. aureus)表现出高浓度和低浓度下的优异抗菌活性,抑制区为 9.30mm,与环丙沙星相比。此外,还对合成纳米复合材料针对选定的酶靶标(即β-内酰胺酶和 DNA 回旋酶)进行了分子对接研究。