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52毫克左炔诺孕酮宫内节育系统在青少年及年轻成年女性中的应用:3年随访

Use of 52-mg Levonorgestrel-Releasing Intrauterine System in Adolescents and Young Adult Women: 3-Year Follow-Up.

作者信息

Oliveira Elaine Cristina Fontes de, Baêta Thaís, Cotta Rossana Cristina Fontes, Rocha Ana Luiza Lunardi

机构信息

Department of Obstetrics and Gynecology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

Departament of Pediatrics, Hospital Vila da Serra, Belo Horizonte, Minas Gerais, Brazil.

出版信息

J Pediatr Adolesc Gynecol. 2023 Feb;36(1):45-50. doi: 10.1016/j.jpag.2022.09.001. Epub 2022 Sep 8.

Abstract

STUDY OBJECTIVE

To evaluate continuance rates, bleeding patterns, and patient satisfaction with 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) use in adolescents and young adult women during the first 3 years of use DESIGN: We conducted an observational prospective study.

SETTING

Family Planning Service of a tertiary hospital in Brazil PARTICIPANTS: One hundred adolescents and young women aged 16-24 years.

INTERVENTION

Insertion of 52-mg LNG-IUS for the main purpose of contraception. Follow-up visits were conducted at 12, 24, and 36 months after insertion.

MAIN OUTCOME MEASURES

Continuance rates, reasons for discontinuation of the method, and women's satisfaction and bleeding patterns RESULTS: Among those who were not lost to follow-up, LNG-IUS continuance rates were 89.1% (82/92), 82.9% (72/87), and 75.3% (64/85) in the first, second, and third years of use, respectively. The main reason for discontinuation was acne, followed by expulsion of/malpositioned LNG-IUS. Other reasons for discontinuation were irregular uterine bleeding, dysmenorrhea, and abdominal pain. The amenorrhea rates were 50%, 54.1%, and 39% at 12, 24, and 36 months, respectively. Spotting rates increased during the first 3 years of use (20.8%, 16.7%, and 26.6%, respectively). Adolescents and young women using the LNG-IUS showed high rates of satisfaction, with 93.9%, 100%, and 96.8% of women being very satisfied/satisfied in the first 3 years of use. Only 2 participants who continued using the LNG-IUS reported being very dissatisfied/dissatisfied in the third year of follow-up.

CONCLUSION

The LNG-IUS showed high rates of continuation and satisfaction in the first 3 years of use in Brazilian adolescents and young adults. Most women reported a favorable bleeding pattern.

摘要

研究目的

评估52毫克左炔诺孕酮宫内节育系统(LNG-IUS)在青少年及年轻成年女性使用的前3年中的续用率、出血模式及患者满意度。

设计

我们开展了一项前瞻性观察研究。

地点

巴西一家三级医院的计划生育服务部门

参与者

100名年龄在16至24岁之间的青少年及年轻女性。

干预措施

插入52毫克LNG-IUS,主要用于避孕。在插入后12、24和36个月进行随访。

主要观察指标

续用率、方法停用原因、女性满意度及出血模式

结果

在未失访的人群中,LNG-IUS在使用的第一年、第二年和第三年的续用率分别为89.1%(82/92)、82.9%(72/87)和75.3%(64/85)。停用的主要原因是痤疮,其次是LNG-IUS排出/位置异常。其他停用原因包括不规则子宫出血、痛经和腹痛。闭经率在12、24和36个月时分别为50%、54.1%和39%。点滴出血率在使用的前3年中有所增加(分别为20.8%、16.7%和26.6%)。使用LNG-IUS的青少年及年轻女性满意度较高,在使用的前3年中,分别有93.9%、100%和96.8%的女性非常满意/满意。在随访的第三年,只有2名继续使用LNG-IUS的参与者报告非常不满意/不满意。

结论

在巴西青少年及年轻成年人中,LNG-IUS在使用的前3年显示出较高的续用率和满意度。大多数女性报告出血模式良好。

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