Pohjola-Sintonen S, Siltanen P, Haapakoski J, Romo M
Eur Heart J. 1987 Apr;8(4):354-9. doi: 10.1093/oxfordjournals.eurheartj.a062285.
In 1970 the Helsinki Coronary Register gathered data on 1191 AMI cases and 470 deaths from AMI of Helsinki residents under 65 years of age. Since then the mortality (deaths within the first 28 days per 1000 habitants of Helsinki) from AMI declined by 1.8% a year during the period 1970-1977, and there were no statistically significant differences in trends between women and men, or between different age groups (P greater than 0.10). The case fatality rate varied from 39% in 1970 to 35% in 1977, and the statistical analysis could not reveal any significant permanent decreasing trend in any age or sex group. These results, together with our previously reported AMI incidence trends, show that at least in 1970-1977 the declining trend in mortality from AMI was due to an equal fall in the incidence of AMI. Therefore there is reason to think that the effect is due to the prevention of AMI, rather than to more effective acute care.
1970年,赫尔辛基冠心病登记处收集了1191例急性心肌梗死(AMI)病例的数据以及470例65岁以下赫尔辛基居民因AMI死亡的数据。从那时起,在1970年至1977年期间,赫尔辛基AMI的死亡率(每1000名居民中在前28天内的死亡人数)每年下降1.8%,并且在女性和男性之间或不同年龄组之间的趋势没有统计学上的显著差异(P大于0.10)。病死率从1970年的39%变化到1977年的35%,并且统计分析未能揭示任何年龄或性别组中有任何显著的持续下降趋势。这些结果,连同我们之前报告的AMI发病率趋势,表明至少在1970年至1977年期间,AMI死亡率的下降趋势是由于AMI发病率的同等下降。因此有理由认为这种效果是由于对AMI的预防,而不是更有效的急性护理。