Hypertrophic cardiomyopathy associated with congenital deaf-mutism.

A family is presented in which there is a high incidence of hypertrophic cardiomyopathy and congenital deaf-mutism. The two abnormalities occurred together in 2 cases, and the syndrome was strongly suspected in a third individual. Hypertrophic cardiomyopathy without deaf-mutism was observed in a further 2 cases. Hypertrophic cardiomyopathy is inherited by an autosomal dominant mode; that occurring together with deaf-mutism is also probably inherited dominantly.