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血液系统相关恶性肿瘤所致嗜酸性粒细胞性皮肤病(综述):一篇病例报告

Haematologic-Related Malignancy-Induced Eosinophilic Dermatoses (He Remained): A Narrative Review.

作者信息

Kar Bikash Ranjan, Agarwal Akash

机构信息

Department of Dermatology IMS and SUM Hospital, Bhubaneswar, Odisha, India.

出版信息

Indian J Dermatol. 2022 Mar-Apr;67(2):206. doi: 10.4103/ijd.ijd_847_21.

Abstract

He remained(Hematologic Related Malignancy- induced Eosinophilic dermatoses) is a new eponym introduced to describe a dermatoses previously described under several terminologies such as eosinophilic dermatoses of haematological malignancy, exaggerated arthropod bite reactions, insect bite-like reactions and T-cell papulosis associated with B-cell malignancies. This chronic relapsing remitting disease has a pleomorphic presentation mimicking a variety of dermatological conditions. The underlying pathophysiology is however poorly understood. It is a paraneoplastic phenomenon hence an underlying haematological malignancy must always be looked for. Response to conventional modalities of treatment such as oral corticosteroids is rapid and satisfactory. Other newer modalities are also in the pipeline. In this manuscript, we present a narrative review of this recently described entity with data identified via a search on 27 September, 2021 in PubMed, EMBASE and MEDLINE using the term 'Eosinophilic dermatoses of haematological malignancy' AND 'Hematologic related malignancy-induced eosinophilic dermatoses'. A total of 67 cases reported in the literature from the year 2012 onward have been included. The literatures pertaining to insect bite-like reactions and exaggerated insect bite hypersensitivity have been excluded in this review.

摘要

血液系统相关恶性肿瘤所致嗜酸性粒细胞性皮肤病是一个新的专用名词,用于描述一种皮肤病,该皮肤病此前曾用多种术语来描述,如血液系统恶性肿瘤的嗜酸性粒细胞性皮肤病、过度的节肢动物叮咬反应、昆虫叮咬样反应以及与B细胞恶性肿瘤相关的T细胞丘疹病。这种慢性复发性疾病有多种表现形式,可模仿多种皮肤病状况。然而,其潜在的病理生理学机制尚不清楚。它是一种副肿瘤现象,因此必须始终寻找潜在的血液系统恶性肿瘤。对传统治疗方式(如口服皮质类固醇)的反应迅速且令人满意。其他更新的治疗方式也在研发中。在本手稿中,我们对这个最近描述的实体进行了叙述性综述,通过在2021年9月27日使用术语“血液系统恶性肿瘤的嗜酸性粒细胞性皮肤病”和“血液系统相关恶性肿瘤所致嗜酸性粒细胞性皮肤病”在PubMed、EMBASE和MEDLINE上进行检索来确定相关数据。本综述纳入了自2012年以来文献报道的共67例病例。本综述排除了与昆虫叮咬样反应和过度昆虫叮咬超敏反应相关的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17dc/9455086/32c63619cf55/IJD-67-206e-g001.jpg

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