Liubimov B I, Iavorskiĭ A N
Farmakol Toksikol. 1987 May-Jun;50(3):71-4.
It was found that lithium oxybutyrate suppresses voluntary consumption of 5% ethanol solution in rats with preliminarily formed alcohol motivation, slows down the formation of alcohol addiction under conditions of forced consumption of 5% ethanol solution and exerts a positive effect on general state of the animals subjected to a long-term action of ethanol by improving the conditioned reflex activity of the central nervous system and stimulating defensive-adaptational mechanisms of the organism.
结果发现,羟丁酸锂可抑制已形成酒精动机的大鼠对5%乙醇溶液的自愿摄取,在强迫摄取5%乙醇溶液的条件下减缓酒精成瘾的形成,并通过改善中枢神经系统的条件反射活动和刺激机体的防御适应机制,对长期受乙醇作用的动物的一般状态产生积极影响。