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慢性粒细胞白血病中的巨大右心房肿块:一例报告及文献综述

A Massive Right Atrial Mass in Chronic Myelogenous Leukaemia: A Case Report and Literature Review.

作者信息

Benjanuwattra Juthipong, Abdelnabi Mahmoud, Rahman Rubayat, Jenkins Leigh Ann

机构信息

Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.

Cardiology and Angiology Unit, Clinical and Experimental Internal Medicine Dept., Medical Research Institute, Alexandria University, Alexandria, Egypt.

出版信息

Eur J Case Rep Intern Med. 2022 Aug 30;9(8):003499. doi: 10.12890/2022_003499. eCollection 2022.

Abstract

UNLABELLED

Right atrial masses are rare and diagnosis can be difficult unless histopathological specimens are obtained. In addition, the clinical course is not well documented, thereby making diagnosis and management challenging. The mass can be associated with haemodynamic instability with the potential to cause obstructive shock and embolism. We present the case of a young woman with untreated chronic myelogenous leukaemia with a massive haemodynamically significant right atrial mass. The usefulness of multimodality imaging and a multidisciplinary approach for diagnosing and treating this condition is highlighted.

LEARNING POINTS

Right atrial mass is rare and can lead to pulmonary embolism and haemodynamic instability.As chronic myelogenous leukaemia is associated with an increased risk of thromboembolism, thrombus should be considered in the differential diagnosis of intracardiac masses.Multimodality imaging is indicated to guide diagnosis and appropriate management; in case of diagnostic uncertainty, histopathology may be needed to obtain a definitive diagnosis.

摘要

未标注

右心房肿块罕见,除非获取组织病理学标本,否则诊断可能困难。此外,临床病程记录不详,因此诊断和管理具有挑战性。该肿块可伴有血流动力学不稳定,有可能导致梗阻性休克和栓塞。我们报告一例患有未经治疗的慢性粒细胞白血病的年轻女性病例,其右心房有一个巨大的具有血流动力学意义的肿块。强调了多模态成像和多学科方法在诊断和治疗这种疾病中的作用。

学习要点

右心房肿块罕见,可导致肺栓塞和血流动力学不稳定。由于慢性粒细胞白血病与血栓栓塞风险增加有关,在心内肿块的鉴别诊断中应考虑血栓。需要多模态成像来指导诊断和适当的管理;在诊断不确定的情况下,可能需要组织病理学来获得明确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f6b/9451512/2127344407b0/3499_Fig1.jpg

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