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阿芬太尼和丙泊酚用于巨大气管内肿瘤患者纤维支气管镜介入治疗诱导麻醉:病例报告

Alfentanil and propofol induced anesthesia for patients with huge endotracheal tumor undergoing fiberoptic bronchoscopic interventional therapy: case report.

作者信息

Zhu Hongyu, Sun Yan, Wang Tingting, Wu Zhilin

机构信息

Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Transl Cancer Res. 2022 Aug;11(8):2946-2952. doi: 10.21037/tcr-22-199.

Abstract

BACKGROUND

There is a high risk of hypoxia or apnea for patients with huge tracheal tumor during general anesthesia. Here we reported two cases of extremely huge endotracheal tumors undergoing fiberoptic bronchoscopic interventional therapy under general anesthesia. We hope the experience will be of reference value for formulating reasonable anesthesia scheme for such critically ill patients.

CASE DESCRIPTION

The two patients were accompanied with severe respiratory distress. And fiberoptic bronchoscopy revealed that the trachea cavity was blocked nearly completely by extremely huge tracheal tumor. Tracheal tumors were scheduled to be removed with fiberoptic bronchoscopic interventional therapy. General anesthesia was inducted with alfentanil and propofol. Then a laryngeal mask was inserted and spontaneous breath was preserved. During the operation, complete airway obstruction occurred, but it was effectively handled by using the fiberoptic bronchoscope to push the tumor and reopen the gap between the mass and the tracheal wall. After the therapy, the patients' symptom of respiratory distress was relieved significantly.

CONCLUSIONS

For patients with huge tracheal tumor that to be handled with fiberoptic bronchoscopic interventional therapy, general anesthesia with spontaneous breath induced by alfentanil and propofol is preferable. The most important, when complete airway blockade occurs during the process, pushing the tumor and reopening the respiratory tract with fiberoptic bronchoscope is a fairly effective solution to enable patients to be reoxygenated.

摘要

背景

巨大气管肿瘤患者在全身麻醉期间存在较高的缺氧或呼吸暂停风险。在此,我们报告两例巨大气管内肿瘤患者在全身麻醉下行纤维支气管镜介入治疗的病例。我们希望该经验对为这类重症患者制定合理的麻醉方案具有参考价值。

病例描述

这两名患者均伴有严重的呼吸窘迫。纤维支气管镜检查显示气管腔几乎完全被巨大的气管肿瘤阻塞。计划通过纤维支气管镜介入治疗切除气管肿瘤。采用阿芬太尼和丙泊酚诱导全身麻醉。然后插入喉罩并保留自主呼吸。手术过程中发生了完全气道阻塞,但通过使用纤维支气管镜推开肿瘤并重新打开肿块与气管壁之间的间隙得到了有效处理。治疗后,患者的呼吸窘迫症状明显缓解。

结论

对于拟行纤维支气管镜介入治疗的巨大气管肿瘤患者,采用阿芬太尼和丙泊酚诱导自主呼吸的全身麻醉较为适宜。最重要的是,在手术过程中发生完全气道阻塞时,用纤维支气管镜推开肿瘤并重新开通呼吸道是使患者恢复氧合的一种相当有效的解决方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ddd/9459539/8e24ae534e89/tcr-11-08-2946-f1.jpg

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