Department of Cardiology, Umraniye Training And Research Hospital, University of Health Sciences, Istanbul, Turkey.
Blood Press Monit. 2022 Dec 1;27(6):378-383. doi: 10.1097/MBP.0000000000000616. Epub 2022 Sep 12.
Left ventricular outflow tract (LVOT) presystolic wave is a novel marker for several cardiac conditions. It is shown to be related to several cardiac conditions. The aim of this study is to investigate the relationship between LVOT presystolic wave and 24-h ambulatory blood pressure measurements.
A total of 194 patients who came to the cardiology outpatient clinic were prospectively enrolled in the study. After demographic and clinical inquiry, blood biochemistry and hemogram tests were performed. Each patient was evaluated with echocardiography and 24-h ambulatory blood pressure measurement. The patients were divided into hypertensive and nonhypertensive groups regarding their ambulatory blood pressure measurements and the LVOT presystolic wave of the groups on echocardiography was compared.
The hypertensive group was significantly older (59.34 ± 11.15 vs. 49.89 ± 15.43; P < 0.001). Presystolic wave presence (96.2 vs. 29.5%; P < 0.001) and velocity (62.23 vs. 29.42; P < 0.001) were higher in patients with hypertension. Blood pressure values and LVOT amplitudes showed a positive correlation ( P < 0.001; r = 0.326). In multivariable logistic regression analysis; age, BMI and the presystolic wave were independently associated with hypertension (odds ratio: 8.09; P < 0.001).
LVOT presystolic wave is associated with systemic hypertension and it could be used as a predictor for systemic hypertensive patients.
左心室流出道（LVOT）收缩前期波是多种心脏疾病的新标志物。它与多种心脏疾病有关。本研究旨在探讨 LVOT 收缩前期波与 24 小时动态血压测量之间的关系。
本研究前瞻性纳入了 194 名前来心内科门诊的患者。在进行人口统计学和临床询问、血液生化和血常规检查后，对每位患者进行超声心动图和 24 小时动态血压测量评估。根据患者的动态血压测量结果，将患者分为高血压组和非高血压组，并比较两组患者的 LVOT 收缩前期波。
高血压组患者年龄明显较大（59.34±11.15 岁比 49.89±15.43 岁；P<0.001）。高血压患者的收缩前期波存在率（96.2%比 29.5%；P<0.001）和速度（62.23 比 29.42；P<0.001）均较高。血压值与 LVOT 幅度呈正相关（P<0.001；r=0.326）。多变量 logistic 回归分析显示，年龄、BMI 和收缩前期波与高血压独立相关（优势比：8.09；P<0.001）。
LVOT 收缩前期波与系统性高血压相关，可作为预测系统性高血压患者的指标。
