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心肌梗死后心脏破裂:尝试手术修复面临的挑战。

Postinfarction cardiac rupture: a challenge to try surgical reparation.

作者信息

Leone A

出版信息

G Ital Cardiol. 1987 Mar;17(3):252-8.

PMID:3609624
Abstract

68 patients deceased from AMI in CCU. They underwent postmortem examination and 12 patients displayed rupture of the free wall of the left ventricle at the sight of the infarction. Clinically, 8 deaths were preceded by an appearance or an increase of chest pain, which was only slightly affected by opiates; 9 patients displayed preterminal sinus rhythm, 2 atrioventricular block and 1 junctional rhythm. In all cases ST-segment was unchanged when the chest pain appeared and death occurred for the 8 patients who felt chest pain in a time interval between 35 and 660 minutes. One could observe a group with early rupture that deceased within 1 hour from the onset of this symptom and 4 patients with late rupture dying in a time-interval between 4 and 11 hours. Pathologically, cardiac hypertrophy and severe coronary alterations were found in all the hearts. Chest pain and unchanged ST-segment at the recorded electrocardiogram often in presence of sinus rhythm in patients showing clinical signs of cardiac hypertrophy should be considered an indication of impending rupture during the course of AMI. Consequently, we must plan a surgical reparation, the only treatment able to save the life of patients who have undergone postinfarction cardiac rupture.

摘要

68例急性心肌梗死患者在冠心病监护病房死亡。他们接受了尸检,其中12例在梗死部位出现左心室游离壁破裂。临床上,8例死亡前出现胸痛或胸痛加重,使用阿片类药物仅有轻微缓解;9例患者临终前出现窦性心律,2例出现房室传导阻滞,1例出现交界性心律。在所有病例中,胸痛出现时ST段无变化,8例感到胸痛的患者在35至660分钟的时间间隔内死亡。可以观察到一组早期破裂患者在出现症状后1小时内死亡,4例晚期破裂患者在4至11小时的时间间隔内死亡。病理检查发现,所有心脏均有心脏肥大和严重的冠状动脉病变。在显示心脏肥大临床体征的患者中,胸痛且记录的心电图ST段无变化,且常伴有窦性心律,应被视为急性心肌梗死过程中即将发生破裂的迹象。因此,我们必须计划进行手术修复,这是唯一能够挽救心肌梗死后心脏破裂患者生命的治疗方法。

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